Quantitative studies on the effects of radiophosphorus (P-32) on bone marrow of Swiss albino mice during postnatal development

Kumar, A.; Srivastava, P.N.

Journal of Radiation Research 18(4): 280-292


ISSN/ISBN: 0449-3060
PMID: 609059
DOI: 10.1269/jrr.18.280
Accession: 068531896

Download citation:  

Article/Abstract emailed within 0-6 h
Payments are secure & encrypted
Powered by Stripe
Powered by PayPal

Radiophosphorus was injected in mice at various stages of development (1 day, 1, 2, 3 and 4 wk) at the dose-rate of 1.0.mu.Ci/g body weight. Animals were autopsied at weekly intervals up to 6 wk, and quantitative studies of pronormoblast, normoblast, granulocyte and lymphocyte counts were made. The erythroid cells showed rapid decrease in their percentage due to irradiation. The myeloid cells underwent accelerated maturation resulting in increased percentage of segmented forms in bone marrow. The percentage of lymphocytes also decreased. Regeneration then occurred, and normal blood forming tissues were found by adulthood.