+ Translate
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Performance of females heterozygous for deficiency of uridine monophosphate synthase

Performance of females heterozygous for deficiency of uridine monophosphate synthase

Journal of Dairy Science 70(5): 945-951

ISSN/ISBN: 0022-0302

PMID: 3597935

DOI: 10.3168/jds.s0022-0302(87)80098-x

Milk orotate concentration was tested for 1451 registered and grade Holsteins from 23 herds. Cows with milk orotate concentration exceeding 200 micrograms/ml were blood-tested for uridine monophosphate synthase activity. Thirty-four cows were diagnosed as deficient in this enzyme, which is necessary for the metabolic conversion of orotate to uridine 5'-monophosphate. To control for genetics, a subset of 33 deficient cows and their 145 normal paternal half-sisters were also analyzed. Milk yield at 305 d, adjusted for age and milking frequency, was significantly affected by the stage of lactation at which the test was done, by the parity of the cow, and by the interaction of the parity of the cow with its diagnosis of uridine monophosphate synthase in both analyses. Twenty-five older, deficient cows yielded the most milk (8118); 8 first-calf, deficient cows the least milk (6810); and 1386 normal cows intermediate amounts. Deficiency effect and interaction of parity with deficiency were not significant for fat. Interaction of parity with deficiency was significant for calving interval. Older, deficient cows had the longest calving intervals; first calf, deficient cows had the shortest calving intervals; and normal cows had intermediate calving intervals. However, deficiency was not associated with milk yield in analysis that considered calving interval as a covariate for milk.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 068585047

Download citation: RISBibTeXText

Related references

Productive and reproductive performance of cattle heterozygous for deficiency of uridine monophosphate synthase. 3rd World Congress on Genetics applied to Livestock Production, Lincoln, Nebraska, USA, July 16-22, 1986 XI Genetics of reproduction, lactation, growth, adaptation, disease, and parasite resistance: 78-83, 1986

A nonradioactive high-performance liquid chromatographic microassay for uridine 5'-monophosphate synthase, orotate phosphoribosyltransferase, and orotidine 5'-monophosphate decarboxylase. Analytical Biochemistry 299(2): 162-168, 2001

Hereditary deficiency DUMPS in cattle (uridine monophosphate synthase deficiency). Tijdschrift Voor Diergeneeskunde 115(20): 958-959, 1990

Detection and incidence of two hereditary abnormalities in Holstein cattle (bovine leukocyte adhesion deficiency and deficiency of uridine monophosphate synthase). Revista Argentina de Produccion Animal 15(3/4): 883-886, 1995

Deficiency of uridine monophosphate synthase among Holstein cattle. Cornell Veterinarian 80(2): 119-122, 1990

Isolation and initial characterization of the single polypeptide that synthesizes uridine 5'-monophosphate from orotate in Ehrlich ascites carcinoma. Purification by tandem affinity chromatography of uridine-5'-monophosphate synthase. Biochemistry 19(20): 4699-4706, 1980

Incidence of bovine leukocyte adhesion deficiency, complex vertebral malformation, and deficiency of uridine-5-monophosphate synthase carriers in Brazilian Girolando cattle. Genetics and Molecular Research: Gmr 12(3): 3186-3192, 2013

Association of deficiency of uridine monophosphate synthase with production and reproduction. Journal of Dairy Science 77(2): 589-597, 1994

A method for diagnosis of deficiency of uridine monophosphate synthase in cattle. Romanian Journal of Biochemistry 43: 81-85, 2006

Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, complex vertebral malformation, bovine citrullinaemia, and factor XI deficiency in Holstein cows reared in Turkey. Acta Veterinaria Scandinavica 52: 56, 2010

Reproductive consequences of deficiency of uridine monophosphate synthase in Holstein cattle. American Journal of Veterinary Research 51(5): 800-802, 1990

Embryonic mortality attributed to inherited deficiency of uridine monophosphate synthase. Journal of Dairy Science 72(11): 3035-3039, 1989

Incidence and inheritance of deficiency for uridine monophosphate synthase in Holstein bulls. Journal of Dairy Science 70(9): 1893-1897, 1987

Deficiency of uridine monophosphate synthase in Holstein cattle: inheritance and body measurements. Journal of Animal Science 64(3): 695-700, 1987

Relationship between genetic merit of Holstein bulls and deficiency of uridine-5'-monophosphate synthase. Journal of Dairy Science 75(7): 2023-2029, 1992