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Dekaris effectiveness in rheumatoid arthritis



Dekaris effectiveness in rheumatoid arthritis



Terapevticheskii Arkhiv 54(6): 95-99



The results of long-term treatment of 67 patients with levamisole (decaris) are presented. The drug was indicated in cases where other agents proved ineffective, i.e., in rheumatoid arthritis associated with focal infection, in a dose of 50-150 mg/day. The maximal effect was attained within 3-5 mo. of continuous treatment. Good results were recorded in 50% of the patients. The efficacy of decaris and D-penicillamine was compared. Decaris has a pronounced antirheumatic effect. It is desirable that the drug be administered in minor doses up to 50 mg/day in conjunction with corticosteroids. The data obtained do not allow the conclusion that decaris possesses immunostimulant or immunosuppressant actions. Further study of the drug mechanism of action in rheumatoid arthritis is required.

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Accession: 068648001

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PMID: 6981224


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