EurekaMag
+ Translate
+ Most Popular
The pigeon tick (Argas reflexus): its biology, ecology, and epidemiological aspects
Prevalence of hemoglobin abnormalities in Kebili (Tunisian South)
Lipogranuloma: a preventable complication of dacryocystorhinostomy
Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency
Bees from the Belgian Congo. The acraensis group of Anthophora
Placing gingival retraction cord
Total serum IgE, allergy skin testing, and the radioallergosorbent test for the diagnosis of allergy in asthmatic children
Acariens plumicoles Analgesoidea parasites des oiseaux du Maroc
Injuries of terminal phalanges of the fingers in children
Biology of flowering and nectar production in pear (Pyrus communis)
Das Reliktvorkommen der Aspisviper (Vipera aspis L.) im Schwarzwald
Hydrological modelling of drained blanket peatland
Pathologic morphology and clinical significance of the anomalous origin of the left circumflex coronary artery from the right coronary artery. General review and autopsy analysis of 30 cases
Cyto genetic analyses of lymphocyte cultures after exposure to calcium cyclamate
Axelrodia riesei, a new characoid fish from Upper Rio Meta in Colombia With remarks concerning the genus Axelrodia and description of a similar, sympatric, Hyphessobrycon-species
Favorable evolution of a case of tuberculosis of pancreas under antibiotic action
RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Parenteral microemulsions: an overview
Temperate pasture: management for grazing and conservation
Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
Thermal expansion and cracking of three confined water-saturated igneous rocks to 800C
Revision of the genera of the tribe Stigmoderini (Coleoptera: Buprestidae) a discussion of phylogenetic relationships
Anal tuberculosis. Report of a case
Gastric tuberculosis in the past and present
Adaptive responses of the cardiovascular system to prolonged spaceflight conditions: assessment with Holter monitoring

Differential expression of genes implicated in liver lipid metabolism in broiler chickens differing in weight


Differential expression of genes implicated in liver lipid metabolism in broiler chickens differing in weight



British Poultry Science 61(1): 10-16



ISSN/ISBN: 0007-1668

PMID: 31630531

DOI: 10.1080/00071668.2019.1680802

1. Lipid parameters and expression of ACACA, APOA1, CPT1A, FASN, FOXO1, LIPG, PPARα and SIRT1 genes involved in lipid metabolism were investigated in two groups of high (HW) and low (LW) weight broilers from the same strain.2. Blood cholesterol and liver triglyceride levels were significantly increased in HW chickens compared to LW broilers, while other parameters, i.e. blood triglyceride, blood HDL/LDL, liver cholesterol and total liver fat showed no significant changes in either group.3. The relative expression of ACACA, APOA1 and CPT1A genes was significantly lower in the liver tissues of HW broilers than in the LW group. The mRNA levels of these three genes showed a significant negative correlation with abdominal fat deposition and live weight of broilers. However, relative expression of FASN, FOXO1, LIPG, PPARα and SIRT1 hepatic genes did not differ among broilers.4. It was concluded that, of eight hepatic genes implicated in lipid metabolism, only the expression of three (ACACA, APOA1 and CPT1A) were significant for fat and leanness within the same strain of chicken. Since reducing body fat is a major goal in the broiler industry, these data can provide fresh insight into the molecular processes underlying the regulation of fat deposition in broilers.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 069434551

Download citation: RISBibTeXText

Related references

β-Casomorphin increases fat deposition in broiler chickens by modulating expression of lipid metabolism genes. Animal: An International Journal of Animal Bioscience 13(4): 777-783, 2019

Effects of soy-lecithin on lipid metabolism and hepatic expression of lipogenic genes in broiler chickens. Livestock Science 8: 1 2, 53-60, 2008

Effect of early feed restriction on hepatic lipid metabolism and expression of lipogenic genes in broiler chickens. Research in Veterinary Science 89(3): 438-444, 2010

Effects of in ovo administration of DHEA on lipid metabolism and hepatic lipogenetic genes expression in broiler chickens during embryonic development. Lipids 42(8): 749-757, 2007

Green tea polyphenols alleviate obesity in broiler chickens through the regulation of lipid-metabolism-related genes and transcription factor expression. Journal of Agricultural and Food Chemistry 61(36): 8565-8572, 2013

Differential regulation of the expression of lipid metabolism-related genes with skeletal muscle type in growing chickens. Comparative Biochemistry and Physiology. Part B Biochemistry and Molecular Biology 189: 1-5, 2015

Gender and Age Effects on the Expression of Genes Related to Lipid Metabolism in Broiler's Liver. Czech Journal of Animal Science 63(3): 103-109, 2018

Flaxseed and Carbohydrase Enzyme Supplementation Alters Hepatic n-3 Polyunsaturated Fatty Acid Molecular Species and Expression of Genes Associated with Lipid Metabolism in Broiler Chickens. Veterinary Sciences 6(1), 2019

Effects of Bacillus licheniformis on the growth performance and expression of lipid metabolism-related genes in broiler chickens challenged with Clostridium perfringens-induced necrotic enteritis. Lipids in Health and Disease 15: 48, 2016

Differential expression of lipid metabolism-related genes and miRNAs in Ctenopharyngodon idella liver in relation to fatty liver induced by high non-protein energy diets. Aquaculture Research 48(8): 4070-4085, 2017

Differential expression of lipid metabolism genes in the liver and adipose tissue of mice treated with evodiamine. Genetics and Molecular Research: Gmr 12(2): 1501-1510, 2013

Transcriptional insights into key genes and pathways controlling muscle lipid metabolism in broiler chickens. Bmc Genomics 20(1): 863, 2019

Study on the differential expression of lipid metabolism-related genes in young LDLR knockout mice liver. Zhonghua Bing Li Xue Za Zhi 37(3): 179-183, 2008

Effects of glucocorticoids on lipid metabolism and AMPK in broiler chickens' liver. Comparative Biochemistry and Physiology. Part B Biochemistry and Molecular Biology 232: 23-30, 2019

Effect of different levels of supplemental yeast on body weight, thyroid hormone metabolism and lipid profile of broiler chickens. Journal of Veterinary Medical Science 75(3): 291-298, 2013