Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on topical therapy in ulcerative colitis

Ginard, D.; Marín-Jiménez, I.; Barreiro-de Acosta, M.; Ricart, E.; Domènech, E.; Gisbert, J.P.; Esteve, M.; Mínguez, M.

Gastroenterologia y Hepatologia 43(2): 97-105


ISSN/ISBN: 0210-5705
PMID: 31839219
DOI: 10.1016/j.gastrohep.2019.10.004
Accession: 069616184

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Although most patients with ulcerative colitis should be given topical treatment, different studies have shown that they are underused in clinical practice. The purpose of this article is to answer 10 specific questions about which drugs are available for topical use in the treatment of ulcerative colitis, and their characteristics in terms of formulation, dosage, presentation, application and proximal distribution of rectal-administered drugs. The efficacy of available topical drugs and the benefits of combining different formulations and routes of administration, and their usefulness during disease remission are evaluated. Finally, a series of recommendations addressed to patients are given on the correct application of topical treatment.