EurekaMag Full Text Articles Chapter 69,734
References:
Bogani, G.; Maltese, G.; Morano, F.; Lorusso, D.; Ditto, A.; Signorelli, M.; Raspagliesi, F. 2017: Assessing the risk of pelvic and para-aortic nodal involvement in apparent early-stage ovarian cancer: a predictors- and nomogram-based analyses. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi70
Signorelli, M.; Bogani, G.; Morano, F.; Maltese, G.; Ditto, A.; Raspagliesi, F.; Lorusso, D. 2017: The impact of chemotherapy-related leukopenia on survival outcomes in locally advanced cervical cancer. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi70
Tavella, K.; Villanucci, A.; Vannini, L.; Rossi, V.; Fantechi, B.; Capone, G.; Putignano, A.L.; Gensini, F.; Porfirio, B.; Amunni, G.; Mazzei, T.; Mini, E.; Papi, L. 2017: Retrospective analysis of 77 patients with ovarian cancer undergoing genetic testing for BRCA1 and BRCA2 mutations. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi71
Lorusso, D.; Nicoletta, C.; Sandro, P.; Roberto, S.; Paolo, S.; Claudio, Z.; Amit, M.O.; Ana, O.; Tamar, S.; Elizabeth, M.S.; Igor, M.B.; Tomasz, H.; Jaroslav, K.; Vladimir, M.; Róbert, P.; Luciana, S.V.; Chris, T.; Caro, U.; Adam, D.; Rebecca, S.K. 2017: ARIEL4: An international, randomised phase 3 study of rucaparib vs chemotherapy as treatment for BRCA1- or BRCA2-mutated, relapsed ovarian cancer. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi71
Bologna, A.; Garcia-Arias, A.; Baldi, L.; Berselli, A.; Pagano, M.; Zanelli, F.; Bisagni, G.; Gervasi, E.; Stridi, G.; Candida, B.; Romagnani, A.; Gnoni, R. 2017: First line treatment with carboplatin-paclitaxel-bevacizumab in ovarian cancer: retrospective review of a single institute experience. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi71
Maccaroni, E.; Giampieri, R.; Del Prete, M.; Principi, G.; Bracci, R.; Calcinari, A.; Della Mora, A.; Bianchi, F.; Belvederesi, L.; Brugiati, C.; Pagliaretta, S.; Pistelli, M.; Savini, A.; Pagliacci, A.; Ballatore, Z.; Bini, F.; Baleani, M.G.; Cantini, L.; Murrone, A.; Berardi, R. 2017: Prognostic impact of CA15-3 pre-treatment levels in ovarian cancer patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi71-Vi72
Alfieri, S.; Bossi, P.; Galbiati, D.; Giannoccaro, M.; Pilotti, S.; Perrone, F.; Paielli, N.; Tonella, L.; Bergamini, C.; Granata, R.; Resteghini, C.; Cavalieri, S.; Iacovelli, N.A.; Orlandi, E.; Locati, L.D.; Licitra, L.; Canevari, S.; De Cecco, L. 2017: Gene-expression profiles of primary and metastatic lesions in head and neck squamous cell carcinoma. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi73
De Cecco, L.; Canevari, S.; Iannò, F.; Locati, L.; Bossi, P.; Licitra, L. 2017: Different signatures of HPV-related oropharynx cancer (OPC) correlate with patients outcome. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi73
Patriarca, C.; Gervasoni, C.; d'Aiuto, A.; Roselli, R.; Petracco, G.; Laudati, A.; Cipolla, M.; Ronchi, P.; Giordano, M. 2017: Plasticity of PD-L1 expression between nodal metastases and primary tumors in p16 negative squamous cell carcinoma of the oral cavity. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi73-Vi74
Maragliano, R.; Fanale, D.; Incorvaia, L.; Caruso, S.; Barraco, N.; Badalamenti, G.; Rizzo, S.; Calò, V.; Perez, A.; Listì, A.; Galvano, A.; Passiglia, F.; Guarini, A.; Bronte, E.; Insalaco, L.; Massihnia, D.; Castellana, L.; Di Piazza, F.; Bazan, V.; Russo, A. 2017: Can the salivary microRNA expression profile help to identify novel biomarkers for oral squamous cell carcinoma detection?. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi73
Cavalieri, S.; Granata, R.; Locati, L.; Bergamini, C.; Alfieri, S.; Resteghini, C.; Galbiati, D.; Orlandi, E.; Iacovelli, N.A.; Calareso, G.; Guzzo, M.; Quattrone, P.; Licitra, L.; Bossi, P. 2017: A single institution twenty-year experience of recurrent or metastatic epithelial non glandular sinonasal cancer. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi74
Granata, R.; Orlandi, E.; Infante, G.; Iacovelli, N.A.; Miceli, R.; Cavallo, A.; Alfieri, S.; Bergamini, C.; Resteghini, C.; Galbiati, D.; Cavalieri, S.; Locati, L.; Tana, S.; Naimo, S.; Fallai, C.; Licitra, L.; Bossi, P. 2017: Subsite-dependent prognostic impact of age in patients with nasopharyngeal and oropharyngeal cancer. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi74
Cau, M.C.; Puxeddu, R.; Tore, G.; Pirri, S.; Pusceddu, Z.; Aste, C.; Carta, F.; Summo, O.; Tandurella, I.; Carta, P.; Aste, M.G.; Defraia, E.; Gutman, G.; Mascia, L.; Mascia, M.G.; Ghiani, M. 2017: Skin rash and response to cetuximab treatment: a retrospective single-center analysis. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi74
Mura, A.; Franceschi, E.; Minichillo, S.; Tosoni, A.; Fioravanti, A.; Talacchi, A.; Volpin, L.; Tallini, G.; De Biase, D.; Visani, M.; Degli Esposti, R.; Genestreti, G.; Pizzolitto, S.; Agati, R.; Bortolotti, C.; Bartolini, S.; Paccapelo, A.; Brandes, A.A. 2017: The role of clinical and molecular characteristics in low grade gliomas. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi75-Vi76
Tosoni, A.; Franceschi, E.; Mura, A.; Minichillo, S.; Pession, A.; De Biase, D.; Danieli, D.; Pizzolitto, S.; Fioravanti, A.; Volpin, L.; Agati, R.; Genestreti, G.; Degli Esposti, R.; Bartolini, S.; Paccapelo, A.; Brandes, A.A. 2017: IDH mutant and 1p19q codeleted low grade gliomas: to treat or not to treat?. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi75
Franceschi, E.; Tosoni, A.; Depenni, R.; Urbini, B.; Faedi, M.; Michiara, M.; Biasini, C.; Giombelli, E.; Pavesi, G.; Zanelli, F.; Cavallo, M.A.; Tosatto, L.; Fioravanti, A.; Zunarelli, E.; Lanza, G.; Bartolini, D.; Silini, E.M.; Brandes, A.A. 2017: Gender and MGMT methylation in glioblastoma patients: interactions in the PERNO prospective study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi75
Cuppari, L.; Lombardi, G.; Evangelista, L.; Pambuku, A.; Saladini, G.; Zagonel, V. 2017: Suspicious for recurrent low and high grade glioma and indeterminate MRI: the role of 18F-DOPA PET/CT. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi76-Vi77
Bergo, E.; Lombardi, G.; Del Bianco, P.; Dal Pos, S.; Berti, F.; Bellu, L.; Pambuku, A.; Zagonel, V. 2017: Worsening of quality of life (QoL), cognitive functions (CF) and psychological status (PSY) can predict radiologic progressive disease (RPD) in glioblastoma (GBM) patients (PTS) treated with radiation therapy (RT) and temozolomide (TMZ): a mono-institutional prospective study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi76
Minichillo, S.; Franceschi, E.; Mura, A.; Tosoni, A.; Tallini, G.; Pession, A.; Foschini, M.; Bortolotti, C.; Danieli, D.; Talacchi, A.; Cirillo, L.; Di Battista, M.; Genestreti, G.; Bartolini, S.; Paccapelo, A.; Brandes, A.A. 2017: The role of treatments in IDH mutant molecular astrocytomas. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi76
Inno, A.; Salgarello, M.; Severi, F.; Pasetto, S.; Romano, L.; Carbognin, G.; Marchetti, F.; Gorgoni, G.; Casolino, R.; Cassandrini, P.; Cirillo, M.; Magarotto, R.; Modena, A.; Nicodemo, M.; Picece, V.; Turazza, M.; Alongi, F.; Valerio, M.; Lunardi, G.; Gori, S. 2017: 18F-sodium fluoride (18F-NaF) PET/CT scan for the assessment of brain metastases (BMs). Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi77
Prelaj, A.; Rebuzzi, S.E.; Giròn Berrìos, J.R.; Pecorari, S.; Fusto, C.; Ferrara, C.; Salvati, M.; Tomao, S.; Bianco, V. 2017: Concomitant versus sequential Fotemustine and Bevacizumab in recurrent malignant gliomas: treatment response and survival outcomes in a retrospective analysis. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi77
Torniai, M.; Savini, A.; Morgese, F.; Rinaldi, S.; Rubini, C.; Santoni, M.; Onorati, S.; Pompili, S.; Onofri, A.; Scarpelli, M.; Berardi, R. 2017: Prognostic relevance of VEGF, VEGFR, IGF and IGFR immunohistochemical expression in gastroenteropancreatic neuroendocrine tumors. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi78
Chillari, F.; Blanco, G.; Russo, A.; Puliafito, I.; Munaò, S.; Battaglia, A.; Franchina, T.; Castorina, L.; Giuffrida, D.; Adamo, V. 2017: Retrospective analysis of the therapeutic efficacy of platinum/etoposide schedules in the treatment of advanced poor differentiated neuroendocrine carcinomas of the lung. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi78
Rossi, E.; Rosania, C.; Ventruto, M.L.; Serrao, S.; Colantuoni, G.; Iannace, C.; Russo, G.; Buono, M.; Gridelli, C. 2017: Genetic counseling for BRCA1/BRCA2 testing. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi79
Villa, F.; Colombo, I.; Crippa, A.; De Martini, G.; Lafranconi, M.; Dell'Oro, S.; Vittimberga, I.; Arnoffi, J.; Guida, F.M.; Villa, S.; Anghilieri, M.; Viganò, C.; Ferrando, P.; De Nittis, G.; Valsecchi, V.; Ardizzoia, A. 2017: Sharing long term follow-up of breast cancer survivors with family physician: a province of Lecco experience. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi79
Gamba, S.; Raffaeli, D.; Marchetti, M.; Russo, L.; Tartari, C.J.; Giaccherini, C.; Verzeroli, C.; Milesi, V.; Brevi, S.; Diani, E.; Vignoli, A.; Sampietro, G.; Malighetti, P.; Spinelli, D.; Falanga, A. 2017: Hypercoagulable state as marker of occult cancer in healthy blood donors: data from HYPERCAN Prospective Study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi79-Vi80
Rapetti, S.G.; Biglia, C.; Capelletto, E.; Galetta, D.; Baffunno, D.; Binato, S.; Marchese, F.; Ferraresi, F.; Novello, S. 2017: Post-survey data about "I do not smoke it", smoking prevention campaign addressed to schools. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi79
Tampellini, M.; Falco, E.; De Rosa, G.; Montarolo, F.; Dacomo, R.; Baratelli, C.; Sperti, E.; Di Maio, M.; Scagliotti, G.V.; Volante, M. 2017: Correlation of PD-L1 staining between primitive tumor and metastasis in advanced colorectal cancer patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi8
Rosanova, M.; De Falco, S.; Attademo, L.; Fiore, G.; De Stefano, A.; Maddalena, C.; De Placido, S.; Carlomagno, C. 2017: Multiple treatment lines and prognosis for metastatic colorectal (mCRC) patients (pts). Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi8-Vi9
Franco, P.; Arcadipane, F.; Racca, P.; Mistrangelo, M.; Cassoni, P.; Morino, M.; Ricardi, U. 2017: Image-guided SIB-IMRT for the treatment of anal cancer patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi8
Carandina, I.; Belluomini, L.; Bonetti, F.; Urbini, B.; Daniel, F.; Lancia, F.; Martella, L.R.; Toma, I.; Moretti, A.; Bannò, E.; Nisi, C.; Da Ros, L.; Frassoldati, A. 2017: Efficacy of anti-EGFR antibodies combined with chemotherapy for elderly patients with RAS wild-type metastatic colorectal cancer: a systematic review and metanalysis. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi8
Pistelli, M.; Bastianelli, L.; Della Mora, A.; Romeo, M.; Ballatore, Z.; Natalucci, V.; Capecci, M.; Ceravolo, M.G.; Serrani, R.; Ricci, M.; Fumelli, D.; Taus, M.; Nicolai, A.; Berardi, R. 2017: Breast cancer secondary prevention: get fit to feel healthy. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi80-Vi81
Gandini, L.; Previtali, P.; Paladini, S.; Allemano, M.C.; Morosi, C.; Tagliabue, E.; Codazzi, D.; Massimino, M. 2017: Occurrence of ultrasound-detected symptomatic and asymptomatic central vein catheter-related thrombosis in pediatric oncology patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi80
Silvana, L.; Leone, S.; Chiara, L.; Anna Maria, G.; Accettura, C.; Saracino, V. 2017: Observational case-control study about the adherence to the Mediterranean diet in elderly oncological patients in Salento. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi80
Mistrangelo, M.; Gallo, F.; Giordano, L.; Solerio, D.; Bau, M.G.; Romaniello, I.; Pietribiasi, F.; Pacquola, M.G.; Castiglione, F.; Sarli, F.; Monagheddu, C.; Ceccarelli, M.; Ciccone, G.; Mistrangelo, M.; Viale, M.; Bertetto, O. 2017: The follow-up and lifestyle (FUCSAM project). Oncology Network of Piemonte and Valle d'Aosta: update 2017. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi80
Barbieri, E.; Gion, M.; Mariani, L.; Stieber, P.; Rubino, D.; Fanti, S.; Baum, R.; Wirtz, R.; Bernardi, A.; Cacciari, N.; Quercia, S.; Lenzi, M.; Cubelli, M.; Pizzirani, C.; Carapelle, M.; Pagliaro, M.; Tomasini, S.; Toracchio, S.; Zamagni, C. 2017: Three-monthly dynamic evaluation of CEA and CA15-3 and 18-FDG PET vs usual practice in the follow-up of early breast cancer patients: a prospective, multicenter, randomized trial (KRONOS - Patient-Oriented New Surveillance-Study Italy). Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi81
D'Ippolito, S.; Shams, M.; Ambrosini, E.; Calì, G.; Pastorelli, D. 2017: The effect of loneliness on cancer mortality. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi82
Bonassi, L.; Ionio, C.; Mascheroni, E.; Liuzzo, A.; Ferrari, F.; Faccio, F.; Peccatori, F.A.; Pravettoni, G. 2017: Risk and protective factors for the construction of prenatal attachment in women with oncological diagnosis during pregnancy: an exploratory observational study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi82-Vi83
Parrino, S.; Sola, M.; Giulio, B.; Rosso, A.; Cinzia, O.; Alessandra, G.; Gurrieri, L.; Stefano, M.; Dicorato, A.; Pascoletti, G.; Fedele, D.; Ceschia, G.; Barazzoni, R. 2017: Evaluating depression in elderly patients with cancer. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi82
Massimiliani, V.; Pellegrino, R.; Donnarumma, L.; Perrone, L.; Riondino, S.; Roselli, M. 2017: Music intervention during chemotherapy infusion reduces anxiety in oncological patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi82
Ratti, M.M.; Bertin, F.; Rossi, A.; Portaluppi, A.; Marconi, M.; Sarno, L.; Verusio, C. 2017: Evaluation OF psychological aspects of taking care cancer patients: a multicentre study on a sample of caregivers. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi83
Airoldi, M.; Denegri, M.; Tosi, C.; Botto, R.; Bovero, A.; Torta, R.; Ieraci, V. 2017: Unmet needs in Head and Neck (H&N) cancer patients: unmet needs, emotional disorders and pain. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi83
Mariotti, S.; Formica, V.; Pellegrino, R.; Nardecchia, A.; Lucchetti, J.; Morelli, A.M.; Laudisi, A.; Morelli, C.; Renzi, N.; Massimiliani, V.; Donnarumma, L.; Riondino, S.; Portarena, I.; Roselli, M. 2017: Evaluation of QoL as a predictor of chemotherapy-induced toxicity. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi83
Barzelloni, M.L.; Serrao, S.; Stanco, A.; Mazza, S.; Gridelli, C. 2017: Role of Theatre as Psychological Support in Cancer Patient. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi84-Vi85
Palazzolo, G.; Schivardi, S.; Simioni, M.T.; Cagnin, M.; Cavallo, R.; Sorarù, M.; Morabito, A.; Sartor, L.; Mion, M.; Beda, M.; Gaion, F.; Sava, T.; Riccardi, L. 2017: Psychological resources and strengths in adults living with lung cancer. A pilot study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi84
Monfredo, M.; Mordenti, P.; di Nunzio, C.; Citterio, C.; Cavanna, L. 2017: The thermometer of distress in oncology. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi84
Verna, L.; Di Pietro, F.R.; Iacono, D.; Peris, F.; Mazzotta, M.; Giusti, R.; Marchetti, P.; Porzio, G. 2017: Incidence of alcoholism among cancer patients undergoing active treatment. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi85
Tirelli, E.; Bin, A.; Bulfone, T.; Simoncini, L.; Zanini, A. 2017: Music and its influence on affectivity and relationships in oncologic and hematologic patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi85
Carapezza, L.; Cordio, S.; Russo, A.; Paladina, I.; Paratore, S.; Longhitano, L.; Bordonaro, R. 2017: Evaluation psychological distress in elderly cancer patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi85-Vi86
Orlandi, E.; Orlandi, E.; Citterio, C.; Cavanna, L. 2017: "I have a cancer, I am ill, it's Sunday, my oncologist is not here, I am despairing." How a telephone call can resolve a great difficulty of cancer patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi85
Tinelli, G.; Chini, C.; Giaquinto, A.; Trotti, E.; Fabbro, G.; Angelonomi, D.; Vallini, I.; Pinotti, G.; Bellani, M.L. 2017: Screening of distress in hospitalized patients: the experience of medical oncology department. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi86-Vi87
Marafante, G.; Ferri, C.; Giuffredi, I.; Bidin, L. 2017: Image and self-esteem: a photo-therapy program to improve body image, increase self-awareness and the expression of emotions in breast cancer patients. A pilot study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi86
Bertagnini, L.; Pacetti, P.; Valsuani, C.; Pennucci, M.C.; Della Seta, R.; Lucchetti, V.; Marchese, C.; Mansanti, L.; Simonini, M.; Mambrini, A. 2017: Cancer as family disease. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi86
Andreis, F.; Gadaldi, E.; Meriggi, F.; Mirandola, M.; Rota, L.; Abeni, C.; Bertocchi, P.; Aroldi, F.; Prochilo, T.; Di Biasi, B.; Ogliosi, C.; Libertini, M.; Noventa, S.; Zaniboni, A. 2017: Dignity Therapy: a new psychoterapeutic approach for people facing advanced disease. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi86
Dessì, A.; Orgiano, L.; Massa, E.; Astara, G.; Madeddu, C.; Pedditzi, E.; Scartozzi, M. 2017: Preliminary data for assessing the impact of psychological stress on the development of primitive tumors or relapses of disease. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi87
Franchina, V.; Ceravolo, F.L.; Franchina, T.; Ricciardi, G.R.R.; Adamo, V. 2017: Photography as a therapeutic tool to re-elaborate "cancer" experience. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi87-Vi88
Sarno, L.; Ratti, M.M.; Soldi, E.; Derevianko, A.; Verusio, C. 2017: Cancer, emotions, and cinema: a preliminary study about the changes experienced by oncological patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi87
Verusio, C.; Ratti, M.M.; Bertin, F.; Portaluppi, A.; Rossi, A.; Sarno, L.; Marconi, M. 2017: Patient relationship training in an integrated perspective: guidelines for psychological intervention. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi88
Caccialanza, R.; Pedrazzoli, P.; Cereda, E.; Colombo, S.; Cappello, S.; Turri, A.; Caraccia, M.; Borioli, V.; Monaco, T.; Imarisio, I.; Klersy, C.; Benazzo, M.; Corbella, F. 2017: Nutritional Counseling with or without Systematic Use of Oral Nutritional Supplements in Head and Neck Cancer Patients Undergoing Radiotherapy. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi89
Stragliotto, S.; Lamberti, E.; Guglieri, I.; Schiavon, S.; Nardi, M.; Procaccio, L.; Brunello, A.; Dadduzio, V.; Galuppo, S.; Zagonel, V.; Murgioni, S. 2017: Simultaneous Care clinic: a three-year monoinstitutional experience. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi89
Lo Dico, S.; Zecca, E.; Brunelli, C.; Bracchi, P.; Vitali, M.; Garassino, M.; Caraceni, A. 2017: Integration of Palliative and Oncology Care in patients with lung and other thoracic cancer: referral criteria and clinical care pathways. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi89-Vi90
Brunelli, C.; Pigni, A.; Mandelli, C.; Bianchi, E.; Ferrigato, L.; Broglia, M.C.; Nanni, O.; Dall'Agata, M.; Sansoni, E.; Cavanna, L.; Dadduzio, V.; Garetto, F.; Pino, M.S.; Bortolussi, R.; Luzzani, M.; Giaretto, L.; Perfetti, E.; Autelitano, C.; Piga, M.A.; Caraceni, A. 2017: Quality of end of life care in patients with pancreatic cancer receiving systematic versus on-demand early palliative care at diagnosis: a secondary outcome analysis from a randomized controlled trial. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi89
Di Bartolomeo, M.; Rosato, G.; Banzi, M.; Pella, N.; Zampino, M.G.; Rimassa, L.; Maiello, E.; Marchetti, P.; Lonardi, S.; Labianca, R.; Zaniboni, A.; Sobrero, A.; Ferrari, D.; Bidoli, P.; Iaffaioli, V.; De Placido, S.; Frassineti, L.; Frustaci, S.; Nicolini, M.; Vernieri, C.; Galli, F. 2017: Metformin and risk recurrence in resected stage II/III colon cancer (CC) patients (pts): subgroup analysis from the TOSCA trial. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi9
Santini, D.; Cremolini, C.; Salvatore, L.; Lonardi, S.; Dell'Aquila, E.; Cattaneo, M.; Loupakis, F.; Rossini, D.; Vincenzi, B.; Ziampiri, S.; Buoro, V.; Tamburini, E.; Basile, D.; Corsi, D.C.; Fioroni, I.; Masi, G.; Borelli, B.; Del Re, M.; Tonini, G.; Falcone, A. 2017: Rechallenge with cetuximab (cet) + irinotecan (iri) in 3rd-line in RAS and BRAF wt metastatic colorectal cancer (mCRC) patients (pts) with acquired resistance to 1st-line cet + iri: the phase II CRICKET study by GONO. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi9
Puzzoni, M.; Demurtas, L.; Giampieri, R.; Ziranu, P.; Pusceddu, V.; Mandolesi, A.; Cremolini, C.; Masi, G.; Gelsomino, F.; Antoniotti, C.; Loretelli, C.; Meriggi, F.; Zaniboni, A.; Falcone, A.; Cascinu, S.; Scartozzi, M. 2017: The role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild type colorectal cancer patients receiving irinotecan/cetuximab. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi9
Fusco, V.; Cabras, M.; Gambino, A.; Bertetto, O.; Numico, G.; De Martino, I.; Alessio, M.; Marinella, M. 2017: Medication-Related Osteonecrosis of JAW (MR-ONJ) After Bisphosphonates, Denosumab and other Drugs in Advanced Cancer Patients: Recent Experience Data from Rete Oncologica Piemonte - Valle D'aosta (North-Western Italy Cancer Network). Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi90
Pellegrino, R.; Mariotti, S.; Spregiaro, S.; Morelli, A.M.; Massimiliani, V.; Donnarumma, L.; Giuliano, G.; Riondino, S.; Roselli, M. 2017: The tailored nutritional counseling in early cancer patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi90-Vi91
Di Maio, M.; Baratelli, C.; Bironzo, P.; Vignani, F.; Bria, E.; Sperti, E.; Marcato, M.; Roila, F. 2017: Efficacy of neurokinin-1 receptor antagonists in the prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in patients receiving carboplatin-based chemotherapy: a systematic review and meta-analysis. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi90
Chini, C.; Bascialla, L.; Gobba, S.; Tuzi, A.; Tinelli, G.; Pomarico, R.; Giani, N.; Flore, M.; Reato, S.; Pinotti, G. 2017: Simultaneous Home Care project for frail advanced cancer patients: a model of integration between no profit and Public Health System. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi90
Bidin, L.; Marafante, G.; Pellacani, B.; Andreoni, A.; Macca, G.; Fiocchi, E.; Boni, L.; Cantù, G.; Garnerone, L.; Sgorbati, R.; Putignano, F.; Belfiglio, B.; Franchi, F.; Corda, C.; La Guzza, C.; Ferri, C.; Giuffredi, I.; Lamanuzzi, E.; Pigaiani, L.; Casini, M.; Mazzoni, M. 2017: Baseline characteristics of cancer Patients demanding integrative oncology (IO) support. The experience of Nuova Oncologia Integrata (NOI), an Italian non-profit organization. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi91
Canale, M.L.; Camerini, A.; Magnacca, M.; Del Meglio, J.; Lilli, A.; Donati, S.; Belli, L.; Lencioni, S.; Amoroso, D.; Casolo, G. 2017: High cumulative anthracycline dose without cardiac toxicity: a study on outlier patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi91
Dognini, G.P.; Petrelli, F.; Destro, M.; Ghilardi, M.; Borgonovo, K.; Cabiddu, M.; Barni, S. 2017: Sunitinb, hypertension and renal function: a monocentric experience. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi91
La Vecchia, M.; Galanti, D.; Volpe, C.; Valerio, M.R. 2017: Role of Anaplus HP in prevention of chemotherapy-induced peripheral neuropathy (CIPN) in patients affected by breast cancer treated with taxane-based adjuvant chemotherapy. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi92
Galanti, D.; La Vecchia, M.; Catarella, M.T.; Crosta, L.; Valerio, M.R. 2017: Micetrin to prevent chemotherapy-induced nausea and fatigue in adjuvant treatment of breast cancer. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi92
Verzeroli, C.; Giaccherini, C.; Marchetti, M.; Masci, G.; Celio, L.; Merelli, B.; Sarmiento, R.; Brevi, S.; Gamba, S.; Milesi, V.; Raffaeli, D.; Russo, L.; Tartari, C.J.; Malighetti, P.; Spinelli, D.; De Braud, F.; Labianca, R.; Gasparini, G.; Santoro, A.; Falanga, A. 2017: Thrombin generation (TG) and D-dimer levels for the identification of cancer patients at higher VTE risk enrolled in the HYPERCAN study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi93
Ridolfi, L.; Elisabetta, P.; Francesco, D.; Alice, R.; Carla, C.; Nicola, G.; Giorgia, G.; Oriana, N.; Alberto, F.; Massimo, G. 2017: Increased frequency of acute reactions to iodinated contrast media after anti-CTLA-4 immunomodulating antibodies in cancer patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi93
Giaccherini, C.; Verzeroli, C.; Marchetti, M.; Masci, G.; Celio, L.; Merelli, B.; Sarmiento, R.; Brevi, S.; Gamba, S.; Milesi, V.; Raffaeli, D.; Russo, L.; Tartari, C.J.; Malighetti, P.; Spinelli, D.; De Braud, F.; Labianca, R.; Gasparini, G.; Santoro, A.; Falanga, A. 2017: Thrombin generation for prediction of early cancer recurrence in breast cancer patients undergoing post-surgical adjuvant therapy: data from the prospective HYPERCAN study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi93
Monti, M.; Campora, S.; Pirondi, S.; Gentili, G.; Guarrera, A.; Taverniti, C.; Cagnazzo, C. 2017: New rules for clinical trials: who will play the game?. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi93-Vi94
Bozza, C.; Gerratana, L.; Basile, D.; De Carlo, E.; Cortiula, F.; Pella, N.; Vitale, M.G.; Bartoletti, M.; Russo, S.; Bonotto, M.; Cinausero, M.; Fanotto, V.; Pelizzari, G.; Minisini, A.M.; Andreetta, C.; Mansutti, M.; Iacono, D.; Sottile, R.; Fasola, G.; Puglisi, F. 2017: Final results from CAMEO-PRO study: complementary and alternative medicine in oncology. physicians inform oncological patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi94
Iachetta, F.; Damato, A.; Bonelli, C.; Romagnani, A.; Banzi, M.; Nicoli, D.; Farnetti, E.; Casali, B.; Pinto, C. 2017: The pre-emptive screening of multiple polymorphisms in gene-encoding dihydropyrimidine dehydrogenase (DPD) improve prevention of toxicity on patients candidate for fluoropyrimidine based-chemotherapy. An experience of the Reggio Emilia Cancer Center. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi94
Altini, M.; Gallegati, D.; Solinas, L.; Gentili, N.; Massa, I.; Amadori, D. 2017: Economic burden of cancer: a population-based cost analysis. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi95
Marzulli, T.; Manzi, P.; Ricci, E.; Alessandrini, G.; De Giorgi, M.; Franchini, D.; Alessandra, D.M.; Brugia, M.; Fiaschini, I. 2017: The role of the clinical risk group classification system in the management of oncologic patients in need of high complexity of care. A pilot study in the local health unit "USL Umbria 2". Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi95
De Troia, B.; Davide, D.; Filipazzi, V.; Isabella, L.; Tosca, N.; Ferrario, S.; Gambaro, A.; Somma, L.; Fasola, C.; Pellegrini, I.; Bombonati, G.; Damiani, E.; Cheli, S.; Falvella, F.S.; Clementi, E.; de Francesco, D.; Cattaneo, M.T. 2017: Genetic Factors Associated with Platinum Toxicity: A Preliminary Study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi95
Vernieri, C.; Milano, M.; Mennitto, A.; Fucà, G.; Rinaldi, L.; Ferrari, B.; Capri, G.; Mariani, G.; Bianchi, G.V.; Longo, V.; de Braud, F. 2017: Safety and metabolic effects of the fasting mimicking diet in cancer patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi96
Gambino, A.; Cabras, M.; Fusco, V.; Bertetto, O.; De Martino, I.; Alessio, M.; Numico, G. 2017: Osteonecrosis of jaw (ONJ) after antiresorptive treatment (bisphosphonates, denosumab) of cancer-treatment induced bone loss (CTIBL): a negligible risk?. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi96
Cortiula, F.; Basile, D.; Gerratana, L.; Bonotto, M.; Ongaro, E.; Garattini, S.K.; Fanotto, V.; Cattaneo, M.; Andreotti, V.J.; Parnofiello, A.; Cocconi, R.; Pecori, D.; Cardellino, G.G.; Casagrande, M.; Ermacora, P.; Giovannoni, M.; Iacono, D.; Puglisi, F.; Aprile, G.; Pella, N.; Fasola, G. 2017: Blood stream infection in cancer patients-device management and epidemiology: the BSIDE study. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi96-Vi97
Larocca, M.; Damato, A.; Rondini, E.; Allegri, E.; Lince, M.P.; Pinto, C. 2017: The impact of social factors on oncology: The experience of the Reggio Emilia Clinical Cancer Center. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi96
Bassanelli, M.; Ceribelli, A.; Giannarelli, D.; Giacinti, S.; Viterbo, A.; Siringo, M.; Poti, G.; Roberto, M.; Macrini, S.; Falcone, R.; Giuli, A.; Di Pietro, F.R.; Aschelter, A.M.; Marchetti, P. 2017: Adjuvant treatment in elderly cancer patients: a multicenter real-life experience. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi97-Vi98
Longobardi, C.; Masini, L.; D'Incà, M. 2017: Can the use of clinical decision support system (CDSS) affect the number of adverse drug reaction (ADR) reports in the oncological patient? A preliminary evaluation of the status quo in Reggio Emilia Oncological Center (CORE) and future perspectives. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi97
Cagnazzo, C.; Arizio, F.; Piccinni Leopardi, M.; Di Costanzo, A.; Crotto, L.; Matocci, R.; Lucarelli, A.; Grassi, E.; Saracino, V.; Fugazza, C.; Cinefra, M.; Marchetti, F.; Taverniti, C.; Stabile, S.; Monti, M.; Marchesi, E. 2017: Clinical trials and risk-based approach: reality or Utopia?. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi97
Di Nunzio, C.; Mordenti, P.; Citterio, C.; Zaffignani, E.; Proietto, M.; Cavanna, L. 2017: Internet in oncology: a new way to improve communication and information?. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi98
Guidi, A.; Luciani, A.; Pagliari, G.; Bocci, B.; Careri, C.; Violati, M.; Blasi, M.; Narracci, M.; Bordin, V.; Caldiera, S.; Zamparelli, G.; Zonato, S.; Cassinelli, G.; Ferrari, D. 2017: Preventive dose reduction of capecitabine in elderly population. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi98
Rampello, G.; Zaiat, M.; Leonardi, P.; Guida, L.; Benenati, S.; Vitiello, R.; Perticone, S.; Titone, V.; Possumato, R.; Siddi, V.; Grisetti, R. 2017: The evolution of palliative care from the oncology patient to the chronic illness. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi98-Vi99
Torchio, M.; Cavalli, C.; Gazo, A.; Bellazzi, R.; Danova, M. 2017: Implementation of the International Myeloma Working Group reccomendations on renal impairment in multiple myeloma patients in routine clinical practice. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi98
Pacetti, P.; Ferrari, C.; Tartarini, R.; Del Freo, A.; Muttini, M.P.; Federici, F.; Crudeli, R.; Mambrini, A. 2017: Nutritional counseling. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi99
Di Lucca, G.; Rossini, C.; Morena, R.; Banfi, L.; Pogliani, C.; Parati, M.C.; Sali, L.; Troisi, A.; Verusio, C. 2017: Association between the development of autoimmune hypothyroidism and objective response to nivolumab: report of two cases. Annals of Oncology: Official Journal of the European Society for Medical Oncology 28 Suppl. 6: Vi99
Pugsley, M.K. 2019: The role of standard for exchange of nonclinical data (SEND) in safety pharmacology. Journal of Pharmacological and Toxicological Methods 99: 106595
Lorenz, H.; Marsch, G.; Germann, P. 2019: In vivo monitoring of gastrointestinal transit: The SmartPill®. Journal of Pharmacological and Toxicological Methods 99: 106595
Jenkinson, S.; Nottebaum, L.; Bassyouni, A.; Lazzaro, J.; Pettersen, B.; Davoren, J. 2019: A role for the M1 muscarinic receptor in gastrointestinal motility. Journal of Pharmacological and Toxicological Methods 99: 106595
Yamada, S.; Yamazaki, D.; Kanda, Y. 2019: Silver nanoparticles inhibits neural differentiation in human iPS Cells. Journal of Pharmacological and Toxicological Methods 99: 106595
Andersen, C.; Dea, S.; Gordon, R.; Guicherit, O.; Zanella, F.; Carromeu, C. 2019: Hight-throughput profiling of seizuregenic liability using human iPSC-derived neuronal 3D cultures. Journal of Pharmacological and Toxicological Methods 99: 106595
Sirenko, O.; Vargas-Hurlston, S.; Chandy, G.; Crittenden, C.; Gordon, R.; Guicherit, O.; Zanella, F.; Carromeu, C. 2019: Functional evaluation of neurotoxic compounds using human iPSC-derived neuronal 3D cultures. Journal of Pharmacological and Toxicological Methods 99: 106595
Tadano, K.; Kazusa, K.; Takamatsu, K.; Naraoka, H.; Takeda, M.; Akashi, M.; Miyagawa, S.; Sawa, Y. 2019: Cardiotoxicity evaluation using three-dimensional cardiac tissues consisting of human iPS cell-derived cardiomyocytes and fibroblasts by cell coating technique. Journal of Pharmacological and Toxicological Methods 99: 106595
Zhang, X.; Abassi, Y.A. 2019: Pharmacological evaluation of disease relevant iPSC-derived cardiomyocyte models. Journal of Pharmacological and Toxicological Methods 99: 106595
Ohtsuki, A.; Stoelzle-Feix, S.; Strassmaier, T.; Okeyo, G.; Bot, C.; Juhasz, K.; Becker, N.; Thomas, U.; Doerr, L.; Rapedius, M.; Brinkwirth, N.; Haarmann, C.; Goetze, T.; Beckler, M.; George, M.; Fertig, N. 2019: Bridging HTS Ion channel and myocyte data. Journal of Pharmacological and Toxicological Methods 99: 106595
Starnes, L.; Hall, A.; Cavallo, A-Lina.; Etal, D.; Gupta, S.; Hirst, C.; Hornberg, E.; Maresca, M.; Hicks, R.; Pointon, A. 2019: A patient-centric CRISPR-Cas9 in vitro cardiovascular safety model to examine genetic variability in calcium handling and its impact on drug-induced cardiotoxicity. Journal of Pharmacological and Toxicological Methods 99: 106595
Sharma, A.Dutt.; McCoy, L.; Willey, H.; Nguyen, H.; Curley, L.; Moore, M. 2019: Novel high-throughput human cells-based co-culture screen for chemotherapeutics induced neurotoxicity. Journal of Pharmacological and Toxicological Methods 99: 106595
Ishibashi, Y.; Odawara, A.; Shirakawa, T.; Kinoshita, K.; Okamura, A.; Miyamoto, N.; Ojima, A.; Kondo, T.; Hando, R.; Morimura, K.; Sato, K.; Suzuki, I. 2019: CSAHi study: Detection of drug-induced seizure-like activities of three convulsants at five facilities using micro-electrode arrays in combination with human iPS cell-derived neurons. Journal of Pharmacological and Toxicological Methods 99: 106595
Strock, C.J. 2019: Utilization of human induced pluripotent stem cell-derived cardiomyocytes on an MEA platform for prediction of liabilities with chronic drug treatment. Journal of Pharmacological and Toxicological Methods 99: 106595
Keung, W.; Lam, Y.Yu.; Chan, C.Ho.; Geng, L.; Cheung, Y-Fai.; Li, R.A. 2019: Modeling the congenital heart condition of pulmonary atresia with intact ventricular septum using human induced pluripotent stem cells. Journal of Pharmacological and Toxicological Methods 99: 106595
Tran, D.D.; Lee, E.K.; Costa, K.D.; Li, R.A. 2019: Scaling human ventricular cardiac chamber models for preclinical screening and monitoring of organ-level pump function. Journal of Pharmacological and Toxicological Methods 99: 106595
Wong, A.O-T.; Chan, C.W.; Costa, K.D.; Li, R.A. 2019: Controlled physiomimetic preload augments inotropic sensitivity and contractile phenotypes in human pluripotent stem cell-derived engineered cardiac tissues and chambers. Journal of Pharmacological and Toxicological Methods 99: 106595
Li, R.A.; Keung, W.; Cashman, T.; Backeris, P.; Johnson, B.V.; Bardot, E.S.; Wong, A.O-T.; Chan, P.K.; Chan, C.W.; Costa, K.D. 2019: "Human heart-in-a-Jar": An electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells. Journal of Pharmacological and Toxicological Methods 99: 106595
Lee, E.K.; Tran, D.D.; Keung, W.; Chan, P.K.; Wong, G.K.; Chan, C.W.; Costa, K.D.; Khine, M.; Li, R.A. 2019: Automated drug classification by machine learning analysis of drug screening data from human pluripotent stem cell-derived engineered cardiac tissue assays. Journal of Pharmacological and Toxicological Methods 99: 106595
Matsuda, N.; Odawara, A.; Okamura, A.; Kinoshita, K.; Shirakawa, T.; Suzuki, I. 2019: Deep learning on MEA data obtained from human iPS cell-derived neurons for predicting seizure risk of new drugs. Journal of Pharmacological and Toxicological Methods 99: 106595
Shum, A.; Wong, A.O-T.; Chan, C.W.; Costa, K.D.; Khine, M.; Kong, C-Wing.; Li, R.A. 2019: Directly visualizing drug-induced arrhythmias with aligned human pluripotent stem cell-based ventricular cardiac anisotropic sheet. Journal of Pharmacological and Toxicological Methods 99: 106595
Wong, A.O-T.; Lieu, D.K.; Wong, G.K.; Gurung, B.; Tse, W.Wai.; Costa, K.D.; Chan, C.W.; Nabhan, J.D.; Li, R.A. 2019: Modeling cardiac dysfunction of Friedreich's ataxia using ventricular sheets, tissues and chambers engineered from human pluripotent stem cells. Journal of Pharmacological and Toxicological Methods 99: 106595
Keung, W.; Chan, P.K.; Backeris, P.; Lee, E.K.; Wong, N.; Wong, G.K.; Chan, C.W.; Fermini, B.; Costa, K.D.; Li, R.A. 2019: Human cardiac ventricular organoid chambers and tissue strips from pluripotent stem cells as a two-tiered assay for inotropic responses: A blinded validation. Journal of Pharmacological and Toxicological Methods 99: 106595
Wei, F.; Cai, C.; Lyn-Cook, B.; Pang, L. 2019: Sex differences in repolarization reserve, a possible mechanism for sex-related differences in drug-induced QT prolongation and torsades de pointes. Journal of Pharmacological and Toxicological Methods 99: 106595
Dea, S.; Biesmans, S.; Mora-Castilla, S.; Romero, S.; Sodhi, N.; Saleh, A.; Woodruff, G.; Harrington, T.; Zanella, F.; Carromeu, C. 2019: High-throughput and high-content safety pharmacology assessments with 3-dimensional human induced pluripotent stem cell-derived cortical spheroid platforms. Journal of Pharmacological and Toxicological Methods 99: 106595
Contu, R.; Padilla, R.; Spangenberg, S.; Fanton, A.; Van Hese, B.; Witty, A.; Zanella, F. 2019: Physiologically-relevant anisotropic 384-well high-throughput hiPSC-derived cardiomyocyte cultures provide better resolution over safety profiles of compounds with known cardiotoxic mechanisms of action. Journal of Pharmacological and Toxicological Methods 99: 106595
Odawara, A.; Ishibashi, Y.; Matsuda, N.; Suzuki, I. 2019: Detection of drug-induced seizure-like activities using MEA system in cultured human iPSC-derived neurons: Report from multi-site pilot study of the HESI NeuTox committee in collaboration with CSAHi and iNCENS. Journal of Pharmacological and Toxicological Methods 99: 106595
Smith, G.; MacQuaide, N.; Nichols, J. 2019: Allowance for diastolic interval distinguishes Na channel block in iPSC-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Naito, A.; Ito, M.; Gao, F.; Furuya, A.; Izumi-Nakaseko, H.; Hagiwara-Nagasawa, M.; Sugiyama, A. 2019: Assessment of the drug-induced toxicity on left ventricular function by pattern-cultured hiPSC-CMs. Journal of Pharmacological and Toxicological Methods 99: 106595
de Korte, T.; van Meer, B.; Garcia, A.Krotenberg.; Tertoolen, L.; Clements, P.J.; Bahinski, A.; Rossman, E.I.; Xu, X.; Turner, S.; Denning, C.; Vlaming, M.; Braam, S.; Mummery, C. 2019: Simultaneous measurement of contraction, voltage and calcium in HIPSC-CMS for the detection of inotropic effects under blinded conditions. Journal of Pharmacological and Toxicological Methods 99: 106595
Famili, F.; Lam, T.Wai.; van Loenen, P.; Nacken, P.; Bras, M.; Honarnejad, S.; Jiang, Y.; Borgdroff, V.; Bohlen, H.; Reijerkerk, A.; Rutjes, H.; Braam, S.; Luerman, G. 2019: High throughput screening in calcium transient assay to assess cardiotoxicity of compounds using hiPSC-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Harlen, K.; Hughes, T.; Fleming, C.; Luerman, G. 2019: Live-cell biosensors reveal novel insight into neurotoxic and cardiotoxic compound mediated cellular stress response. Journal of Pharmacological and Toxicological Methods 99: 106595
Lu, H.Rong.; Zeng, H.; Kettenhofen, R.; Guo, L.; Kopljar, I.; Ammel; Fetene, T.; Pierson, J.; Gallacher, D.J. 2019: Detecting drug-induced long QT and arrhythmic risks with 28 CIPA compounds using a Ca 2+ transient assay in human induced pluripotent stem cell-derived cardiomyocytes: A consortium from 3 sites. Journal of Pharmacological and Toxicological Methods 99: 106595
Kondo, T.; Chikamoto, J.; Oka, H.; Morita, F.; Okazaki, S. 2019: MEA analysis using human iPS cell-derived dopaminergic neurons as a model to assess central nervous system effects of pharmaceutical compounds. Journal of Pharmacological and Toxicological Methods 99: 106595
El-Haou, S.; Kirby, R.W.; Webdale, L.; Rogers, M. 2019: Assessment of human induced pluripotent stem-cell derived cardiomyocytes for evaluating drug induced arrhythmias with multi-electrode array. Journal of Pharmacological and Toxicological Methods 99: 106595
Huang, M.; Shi, H.; Levesque, P. 2019: Characterization of contractile properties of hIPSC-CMs cultured with or without fibroblast and chronic electrical stimulation. Journal of Pharmacological and Toxicological Methods 99: 106595
Takasuna, K.; Honda, Y.; Asayama, M.; Mitsui, H.; Nagano, C.; Kato, N.; Hisada, S. 2019: Comprehensive in vitro cardiac safety assessment using human stem cell technology (CSAHi-The second stage) -Ca 2+ transient platform. Journal of Pharmacological and Toxicological Methods 99: 106595
Linder, P.; Beckler, M.; Doerr, L.; Stoelzle-Feix, S.; Fertig, N.; Jung, A.; Staat, M.; Gossmann, M. 2019: A new in vitro tool to investigate cardiac contractility under physiological mechanical conditions. Journal of Pharmacological and Toxicological Methods 99: 106595
Aoyama, N.; Liu, J.; Lor, S.; Feaster, T.K.; Hilcove, S.; Jones, E. 2019: Assessment of hypertrophic cardiomyopathy using human induced pluripotent stem cell-derived cardiomyocytes reveals abnormal excitation contraction coupling. Journal of Pharmacological and Toxicological Methods 99: 106595
Hori, K.; Kawahara, N.; Kinoshita, K.; Tooi, N.; Yamamoto, Y.; Yabuuchi, M.; Uda, J.; Nakatsuji, N.; Aiba, K. 2019: 3D-Cell device with aligned and multilayered myocardial tissue derived from iPS-cells for predictive drug safety applications. Journal of Pharmacological and Toxicological Methods 99: 106595
Zeng, H.; Wang, J.; Clouse, H.; Lagrutta, A.; Sannajust, F. 2019: Resolving the reversed rate effect of calcium channel blockers on human induced pluripotent stem cell-derived cardiomyocytes and the impact on in vitro cardiac safety evaluation. Journal of Pharmacological and Toxicological Methods 99: 106595
Stevens, D.W.; Wong, L.P.; Schutt, L.; Gelzleichter, T. 2019: Inclusion of telemetry cardiovascular parameters in small molecule repeat-dose toxicity studies, a potential refinement in animal use. Journal of Pharmacological and Toxicological Methods 99: 106595
Kinter, L.B.; Johnson, D.K. 2019: External passive heat-generating devises and body temperature support in small animals. Journal of Pharmacological and Toxicological Methods 99: 106595
Fermini, B.; Sullivan, D.D.; Chal, J.; Fine, E.J.; Coyne, S.T.; King, A.; Johnson, J.; Hernandez, A.Ulan.; Obata, C.F.; Coyne, K.P. 2019: Clinical trials-in-a-dish: Different inter-individual drug responses for calcium handling and electrophysiology in a cohort of hiPSC-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Kinter, L.B.; Terazi, M.; DeTolla, L.; Johnson, D.K. 2019: The harm in harm benefit analysis terminology and safety pharmacology. Journal of Pharmacological and Toxicological Methods 99: 106595
Kolasa, Yël.; Georges, J-Philippe.; Bastogne, T. 2019: Computer-aided design of ECG telemetry systems for online cardiac monitoring. Journal of Pharmacological and Toxicological Methods 99: 106595
Harris, P.; Gerwin, P.; Colangelo, J.; Petrella, C.; Rosado, I.; Singer, L.; Fernandez, R.; Wisialowski, T. 2019: Cardiovascular assessment during paired feeding in telemetry implanted monkeys. Journal of Pharmacological and Toxicological Methods 99: 106595
Ackley, D.; Abernathy, M.; Chaves, A.; Damiano, B.; Delaunois, A.; Foley, M.; Greiter-Wilke, A.; Guillon, J-Michel.; Maher, J.; Monticello, T.; Pannirselvam, M.; Renninger, J.; Vargas, H. 2019: Current nonclinical in vivo safety pharmacology testing enables safe entry to first-in-human clinical trials: The IQ consortium nonclinical to clinical translational database. Journal of Pharmacological and Toxicological Methods 99: 106595
Bujold, K.; Pfeiffer, J.; Authier, S.; Malcolmson, R.; Fink, J.; Tepper, J. 2019: Novel Methods for the Assessment of Safety Pharmacology and Toxicology Parameters in Anesthetized and Ventilated Dogs Receiving Inhaled Drugs. Journal of Pharmacological and Toxicological Methods 99: 106595
Tang, H-Ming. 2019: Evaluation of respiratory rate measurements derived from blood pressure waveforms in telemetered dogs. Journal of Pharmacological and Toxicological Methods 99: 106595
Dinklo, T.; Waiz, D.; Roberts, S.; Sturm, S.; Jenni, R.; Aegler, M.; Greiter-Wilke, A. 2019: Rodent respiratory findings with mGlu5 positive allosteric modulator RG7342, translation to non-rodent and man. Journal of Pharmacological and Toxicological Methods 99: 106595
Fares, R.; Bory, C.; Valgalier, C.; Baudet, S. 2019: Implementation of DSI FinePointe® whole body plethysmography method in freely moving rats. Journal of Pharmacological and Toxicological Methods 99: 106595
Xia, X.; Wu, R.; An, S.; Li, R.; Mcpherson, S. 2019: Comparison of different QTc formulae for correction of QT interval in cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods 99: 106595
Roberts, S.; Greiter-Wilke, A.; Waiz, D.; Jenni, R.; Weile, C.; Zihlmann, M.; Tessier, Y.; Braendli-Baiocco, A.; Festag, M. 2019: Cardiovascular effects of RTR2996, a single stranded oligonucleotide, in the minipig. Journal of Pharmacological and Toxicological Methods 99: 106595
Sheffield, M.E.; Ashcroft-Hawley, K. 2019: Assessment of relative sensitivities of crossover and ascending-dose study designs for cardiovascular telemetry evaluation in cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods 99: 106595
Kremer, J.; Kopelke, K.; Sielaff, A.; Taschwer, M.; Nichols, J. 2019: PhysioTel M-series telemetry is a viable alternative to jacketed telemetry for continuous cardiovascular data collection on toxicology studies. Journal of Pharmacological and Toxicological Methods 99: 106595
Loiodice, S.; Modolo, J.; Cayre, E.; Denibaud, A-Sophie.; Rion, B.; Viardot, G.; L'Hostis, P.; Wendling, F.; La Rochelle, C.Drieu. 2019: Evaluation of seizure liabilities of epileptogenic but non-convulsive agents in rats. Journal of Pharmacological and Toxicological Methods 99: 106595
Geist, B.; Youngblood, B.L.; Ueyama, Y.; LaRose, A.; Hamlin, R.; Evanchik, M.J.; Del Rio, C. 2019: Telemetered left-ventricular pressure in Yucatan mini-pigs: Chronic evaluation in a novel genetic model of non-obstructed hypertrophic cardiomyopathy. Journal of Pharmacological and Toxicological Methods 99: 106595
Sadekova, N.; Norton, K. 2019: Cardiovascular assessments in juvenile monkeys using jacketed telemetry: Background data and the effects of heart rate on QT correction. Journal of Pharmacological and Toxicological Methods 99: 106595
Bory, C.; Coquard, D.; Boucheix, O.; Baudet, S. 2019: Validation of gluteus medius muscle electromyographic (EMG) recording by telemetry in socialized cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods 99: 106595
El Amrani, A-Ilah.; Huang, H.; Loriot, S.; El Amrani, F.; Singh, P.; Authier, S.; Forster, R. 2019: Dual effect of clonidine on QT interval duration and body temperature in cynomolgus monkeys: QT correction formula for changes in core body temperature. Journal of Pharmacological and Toxicological Methods 99: 106595
de Seadi Pereira, P.Juliana.Brizuela.; Pouliot, M.; Easter, A.; Harper, C.; Prefontaine, A.; Miraucourt, L.; Tan, W.; Maghezzi, M.Said.; Wallis, R.; Authier, S. 2019: Occurrence of spontaneous arrhythmias in freely moving non-treated healthy telemetered Sprague-Dawley rats. Journal of Pharmacological and Toxicological Methods 99: 106595
Miraucourt, L.; Accardi, M.; Huang, H.; Authier, S. 2019: Proof of concept comprehensive ex vivo neurological assay. Journal of Pharmacological and Toxicological Methods 99: 106595
Ardrey, T.; Ross, J.; Waines, M.; Campbell, T.; Patel, P.; Roche, B. 2019: Assessment of multiple positive controls in the Langendorff isolated heart assay and how they translate to whole animal. Journal of Pharmacological and Toxicological Methods 99: 106595
Shaffer, J.; Ross, J.; Obejero-Paz, C.A.; Waines, M.; Bruening-Wright, A.; Roche, B. 2019: Can cardiovascular liabilities be detected earlier in drug development? Assessing the translation of tyrosine kinase inhibitors from cardiomyocytes and isolated hearts to whole animal. Journal of Pharmacological and Toxicological Methods 99: 106595
Payseur, J.D.; Wu, X.; Turner, S.L.; Bayrak, K.; Bahinski, A.; Rossman, E.I. 2019: The effect of DMSO on the contraction and relaxation of isolated thoracic aorta of the CRL:WI(Han) rat. Journal of Pharmacological and Toxicological Methods 99: 106595
Kim, A.H.; Korpal, M.; Hukkanen, R.; Rioux, N.; Warmuth, M.; Smith, P. 2019: H3B-6545, a selective estrogen receptor covalent antagonist, prevents bone loss in ovariectomized Sprague-Dawley rats. Journal of Pharmacological and Toxicological Methods 99: 106595
Inutsuka, T.; Okamoto, M.; Yoshimi, Y. 2019: New approach for neuropharmacology profile: In-situ real-time neuropharmacology monitoring by imaging technique using the molecularly imprinted polymers (MIPs) probe. Journal of Pharmacological and Toxicological Methods 99: 106595
Detwiler, T.; Regan, C.; Regan, H.; Sitko, G.; Sannajust, F. 2019: Development and characterization of a nerve conduction model in anesthetized non-human primates as a tool to assess compound-dependent peripheral nervous system risk. Journal of Pharmacological and Toxicological Methods 99: 106595
Rolf, M.G.; Purbrick, S.; Antonsson, M.; Seeliger, F.; Billger, M. 2019: Integrating efficacy and safety: Telemetry and echocardiography in a pig model of myocardial infarction. Journal of Pharmacological and Toxicological Methods 99: 106595
Van Ammel, K.; Urmaliya, V.; Lu, H.Rong.; Rohrbacher, J.; Kopljar, I.; Jansen, H.; Gallacher, D.J.; Teisman, A. 2019: A translational analysis: In vitro hiPSC cardiomyocytes to human phase I analysis for a set of reference compounds with different QT/TdP risk categories. Journal of Pharmacological and Toxicological Methods 99: 106595
Regan, C.; Fanelli, P.; Regan, H.; Detwiler, T.; Morissette, P.; Gruver, S.; Sannajust, F. 2019: Measurement of heart rate variability (HRV) and spontaneous baroreflex sensitivity (sBRS) provides valuable information on compound-dependent cardiovascular effects to enhance safety risk assessment. Journal of Pharmacological and Toxicological Methods 99: 106595
Regan, C.; Regan, H.; Fanelli, P.; Sannajust, F. 2019: Getting more from blood pressure signals: Use of pulse wave analysis (PWA) to enable greater insight to compound-dependent hemodynamic effects. Journal of Pharmacological and Toxicological Methods 99: 106595
Pointon, A.; Rolf, M.G. 2019: Moving from detection of cardiovascular liabilities to quantitative mechanistic understanding: Concepts, challenges and opportunities. Journal of Pharmacological and Toxicological Methods 99: 106595
Teisman, A.; Ammel; Urmaliya, V.; Gallacher, D.J. 2019: A translational research approach for cardiovascular safety assessment at Janssen. Journal of Pharmacological and Toxicological Methods 99: 106595
Roche, B.; Ross, J.; Obejero-Paz, C.A.; Kramer, J. 2019: Is the current non-clinical drug development safety paradigm effective for assessing cardiovascular liabilities?. Journal of Pharmacological and Toxicological Methods 99: 106595
Regan, C.; Delahanty, T.; Brockway, R.; Fanelli, P.; Regan, H.; Detwiler, T.; Gruver, S.; Miller, G.; Sannajust, F. 2019: Evaluation of clinically-relevant proarrhythmic ECG biomarkers in conscious beagle dogs using a newly developed multiple lead ECG telemetry implant. Journal of Pharmacological and Toxicological Methods 99: 106595
Arimura, Z.; Gao, B.; Fang, M.; Qu, Y.; Vargas, H. 2019: Evaluation of cardiac function after cardioplegic treatment in isolated rabbit hearts. Journal of Pharmacological and Toxicological Methods 99: 106595
Urmaliya, V.; Van Ammel, K.; Rohrbacher, J.; van der Linde, H.; Lu, H.Rong.; Jansen, H.; Gallacher, D.J.; Teisman, A. 2019: An integrated translational analysis summary: Prediction of HERG, isolated wedge preparation, anaesthetized guinea pig and dog towards phase I clinical data for drugs with different QT/TdP risk categories. Journal of Pharmacological and Toxicological Methods 99: 106595
Jansen, H.; Urmaliya, V.; Van Ammel, K.; van der Linde, H.; Rohrbacher, J.; Teisman, A.; Gallacher, D.J. 2019: Translational research: What can we learn from the predictability of anesthetized guinea-pig and dog models for cardiovascular safety findings in man?. Journal of Pharmacological and Toxicological Methods 99: 106595
Rohrbacher, J.; Jansen, H.; Van Ammel, K.; Lu, H.Rong.; Urmaliya, V.; Teisman, A.; Gallacher, D.J. 2019: A translational analysis: Cardiac ion channels and isolated rabbit left ventricular wedge in predicting CV safety risk. Journal of Pharmacological and Toxicological Methods 99: 106595
Wisialowski, T.; Gorczyca, W.; Harris, P. 2019: Comparison of effects of moxifloxacin on QT, JTpeak and Tpe in conscious telemetered dogs and nonhuman primates. Journal of Pharmacological and Toxicological Methods 99: 106595
Wang, S.; Valentine, P.A.; Cato, M.J.; Bahinski, A.; Chaudhary, K.W. 2019: Comparison of in silico action potential modeling (AP-Predict) and the hiPSc-CM MEA assay in predicting drug-induced cardiotoxicity. Journal of Pharmacological and Toxicological Methods 99: 106595
Gao, X.; Daily, N.; Carlson, B.E.; Pang, L.; Wakatsuki, T. 2019: Bridging the gap between data from human iPSC-derived cardiomyocytes and CiPA simulation. Journal of Pharmacological and Toxicological Methods 99: 106595
Llopis, J.; Cano, J.; Gomis-Tena, J.; Romero, L.; Sanz, F.; Pastor, M.; Trenor, B.; Saiz, J. 2019: In silico assay for preclinical assessment of drug proarrhythmicity. Journal of Pharmacological and Toxicological Methods 99: 106595
Qu, Y.; Vargas, H.; Rodriguez, B.; Zhou, X.; Passini, E.; Liu, Y.; Bueno-Orovio, A. 2019: Pro-arrhythmic risk assessment with a population model of human ventricular myocyte action potentials. Journal of Pharmacological and Toxicological Methods 99: 106595
Taylor, A.; Wardhaugh, C.; Bryant, M.; Smith, G. 2019: Correlation of optical action potential data from CiPA myocyte study with in vivo arrhythmia parameters. Journal of Pharmacological and Toxicological Methods 99: 106595
Kaushik, E.P. 2019: Concordance of Ion Channel, Cardiomyocyte, and Preclinical Species in Proarrhythmia Cardiac Safety Evaluation. Journal of Pharmacological and Toxicological Methods 99: 106595
Wisialowski, T.; Cordes, J.; Pettersen, B.; Flynn, D. 2019: Hypothermia-induced QTc prolongation in non-human primates; Why you should measure body temperature in cardiovascular safety studies. Journal of Pharmacological and Toxicological Methods 99: 106595
Valentin, J-Pierre.; Guillon, J-Michel.; Hoffman, P.K.; Ortemann-Renon, C.; Koerner, J.; Pierson, J.; Gintant, G.A.; Willard, J.; Skinner, M.; Wisialowski, T.; Pugsley, M. 2019: Prediction of drug-effects on cardiac repolarization in humans: What can we learn from the past to refine our drug discovery strategies?. Journal of Pharmacological and Toxicological Methods 99: 106595
Gorczyca, W.; Wisialowski, T.; Colangelo, J. 2019: Use of PK/PD modelling of nonclinical cardiovascular data to aid in ex vivo-to-in vivo and cross-species translation. Journal of Pharmacological and Toxicological Methods 99: 106595
Bernardo, V.; Tyszkiewicz, C.; Bhatt, S.; Wisialowski, T.; Goody, S. 2019: Comparison of telemetry-derived activity generated from rodent cardiovascular studies with quantitative open field locomotor activity. Journal of Pharmacological and Toxicological Methods 99: 106595
Yoshinaga, T.; Kubo, T.; Asakura, K.; Abe, Y.; Saitou, R.; Shirakawa, T.; Furukawa, Y.; Ashihara, T. 2019: Challenge for the in silico translation of Na channel blockade effects on human-ECG parameters. Journal of Pharmacological and Toxicological Methods 99: 106595
Wisialowski, T.; Jenkinson, S.; Gosink, M. 2019: An in silico predictive model for TdP based on multiple ion channel inhibition. Journal of Pharmacological and Toxicological Methods 99: 106595
Derakhchan, K.; Reeves, R.; Keefe, D.; Parker, S.; Carey, G. 2019: Evaluation of cardiovascular risk related to a monoclonal antibody mediated increase in vascular endothelial growth factor in conscious normal rats. Journal of Pharmacological and Toxicological Methods 99: 106595
Passini, E.; Britton, O.J.; Bueno-Orovio, A.; Rodriguez, B. 2019: Human in silico trials on drug-induced changes in electrophysiology and calcium dynamics using the virtual assay software. Journal of Pharmacological and Toxicological Methods 99: 106595
Morissette, P.; Imredy, J.; Zhai, J.; Travis, J.; Fanelli, P.; Dech, S.; Regan, C.; Bueno-Orovio, A.; Passini, E.; Rodriguez, B.; Sannajust, F. 2019: Impact of in vitro ion channel protocols when assessing cardiac pro-arrhythmic risk with in silico models. Journal of Pharmacological and Toxicological Methods 99: 106595
Margiotta-Casaluci, L.; Dusza, H.; Moreira, Iês.; Winter, M.J.; Prior, H. 2019: Development of an adverse outcome pathway (AOP) for cardiotoxicity mediated by the blockade of L-type calcium channels. Journal of Pharmacological and Toxicological Methods 99: 106595
Ether, N.; Lauver, A.; Bailie, M.; Leishman, D. 2019: Improving the prediction of torsade de pointes risk during drug discovery and development. Journal of Pharmacological and Toxicological Methods 99: 106595
Lauver, A.; Abolibdeh, B.; Bailie, M.; Leishman, D. 2019: Action potential plateau phase metrics in predictive models of arrhythmia potential. Journal of Pharmacological and Toxicological Methods 99: 106595
Kubo, H.; Kagawa, Y.; Hinata, Y.; Baba, H.; Narita, R.; Shioyama, T.; Sasaki, D.; Matsuura, K.; Daily, N.; Wakatsuki, T.; Shimizu, T.; Kobayashi, N. 2019: Validation of cardiac cell sheet-based contractile force measurement system for pharmacological safety assessment. Journal of Pharmacological and Toxicological Methods 99: 106595
Senese, P.B.; Doherty, K.; Bullough, D.; Carreira, V.; Gralinski, M. 2019: Effect of TSN3015 on the development of pulmonary arterial hypertension in male Sprague-Dawley rats. Journal of Pharmacological and Toxicological Methods 99: 106595
Del Rio, C.L.; Zambataro, C.; Bogie, H.; Yucel, A.J.; Ferguson, B.; Henze, M.P.; Fernandes, S.; Evanchik, M.J. 2019: Simultaneous integration of telemetered left-ventricular pressure and echocardiography in rats: Minimally-invasive serial pressure-volume relationships in the setting of normal and impaired diastolic function. Journal of Pharmacological and Toxicological Methods 99: 106595
Brown, A.J.; Grimes, J.; Desai, S.; Santos, R.Moita.; Llobet, A.Isidro.; Mason, A.; Wu, Z.; Wolfe, L.; Wilk, D.Dalmas.; Green, A.; Charter, N. 2019: The mast cell receptor MrgX2 and drug-induced anaphylaxis. Journal of Pharmacological and Toxicological Methods 99: 106595
Berg, E.L.; Velichko, S.; Nguyen, D.T.; Melrose, J.; O'Mahony, A. 2019: Phenotypic profiling for understanding mechanisms of cardiovascular adverse reactions. Journal of Pharmacological and Toxicological Methods 99: 106595
Voss, K.; Shaffer, J.; Foust, S.; Campbell, T.; Wilson, G.; White, M.; Roche, B. 2019: Closing the gap preclinically to derisk the potential for serotonin toxicity: Was that a twitch I see?. Journal of Pharmacological and Toxicological Methods 99: 106595
Trujillo, M.; Noji, S.; Satoko, Y.; Cheng, G.; Suzuki, I. 2019: A high-throughput acute brain slice micro-electrode array assay for toxicology screening. Journal of Pharmacological and Toxicological Methods 99: 106595
Bradley, J.A.; Strock, C.J. 2019: Evaluation of pilocarpine in multiple neuronal cell types using microelectrode array. Journal of Pharmacological and Toxicological Methods 99: 106595
Metea, M.; Lyng, G.D.; Mena, J.D. 2019: Nerve conduction assessments detect early changes in sensory and motor nerve function in a preclinical mouse model of chemotherapy-induced peripheral neuropathy (CIPN). Journal of Pharmacological and Toxicological Methods 99: 106595
Hyun, S-Ae.; Lee, Y-Ju.; Kang, S-Woong.; Shim, H-Eun.; Seo, J-Wook. 2019: The comparative study of 2D and 3D cellular environment on human-induced pluripotent stem cell-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Delaunois, A.; Rjasanow, A.; Hebeisen, S.; Passini, E.; Rodriguez, B.; Smith, G.; Bryant, M.; Valentin, J-Pierre. 2019: An initial company experience gained from using preclinical CiPA testing paradigm in a drug discovery setting: Challenges still lying ahead. Journal of Pharmacological and Toxicological Methods 99: 106595
Batista, L.; Doerr, L.; Juhasz, K.; Stoelzle-Feix, S.; Beckler, M.; Bastogne, T. 2019: Mixed-effects modeling for concentration effect profiling in cardiomyocyte contractility assays. Journal of Pharmacological and Toxicological Methods 99: 106595
Batista, L.; Contu, R.; Van Hese, B.; Zanella, F.; Bastogne, T. 2019: Automated classification of early afterdepolarizations grades in FLIPR calcium assays. Journal of Pharmacological and Toxicological Methods 99: 106595
Guyot, P.; Djermoune, E-Hadi.; Bastogne, T. 2019: Assessment of non-negative matrix factorization for the preprocessing of long-term ECG. Journal of Pharmacological and Toxicological Methods 99: 106595
Batista, L.; Bastogne, T. 2019: Robust estimation of field potential duration in multi-electrode array signals. Journal of Pharmacological and Toxicological Methods 99: 106595
Huang, H.; Boulay, E.; Menard, A.; Tan, W.; Dubuc-Mageau, M.; Sanfacon, A.; Accardi, M.; Miraucourt, L.; Authier, S. 2019: Consensus, debates and controversies with nonclinical proarrhythmia assays. Journal of Pharmacological and Toxicological Methods 99: 106595
Bae, I.S.; Wang, E.B.; Abernathy, M.; Leishman, D. 2019: Modeling thorough QT outcomes for FDA-approved small molecules from 2005 to 2017. Journal of Pharmacological and Toxicological Methods 99: 106595
Wang, E.B.; Abernathy, M.; Leishman, D. 2019: An evaluation of patch-clamp protocols simulated using Markov models. Journal of Pharmacological and Toxicological Methods 99: 106595
Wang, E.B.; Abernathy, M.; Leishman, D. 2019: Model-based assessment of QT interval correction methods. Journal of Pharmacological and Toxicological Methods 99: 106595
Simjee, S.U.; Jawed, H.; Ali, S.Uzair.S. 2019: Inhibition of C-Fos protein and mRNA expression in the brain of adjuvant-induced arthritic rats following treatment with N-(2-hydroxy phenyl) acetamide. Journal of Pharmacological and Toxicological Methods 99: 106595
Nguyen, H.; McCoy, L.; Willey, H.; Sharma, A.Dutt.; Curley, L.; Moore, M. 2019: Nerve-on-a-chip platform for assessing chemotherapy-induced peripheral neuropathy. Journal of Pharmacological and Toxicological Methods 99: 106595
Kreir, M.; Teuns, G.; Lu, H.Rong.; Gallacher, D.J. 2019: Are human iPSC-derived neurons a good tool to detect seizurogenic drugs?. Journal of Pharmacological and Toxicological Methods 99: 106595
Kearney, K.R.; Jenkins, C.J.; Adkins, N.A.; Appleby, C.S.; Metea, M.; Richardson, C.; Roche, B. 2019: Surface lead EEGs: Will it stick?. Journal of Pharmacological and Toxicological Methods 99: 106595
Bader, B.M.; Jügelt, K.; Schultz, L.; Anson, B.; Clemens, M.; Schröder, O. 2019: Functional in vitro HTS seizure prediction with human and mouse neurons growing on microelectrode arrays analyzed by artificial intelligence-based methods. Journal of Pharmacological and Toxicological Methods 99: 106595
Dinklo, T.; Garces, P.; Chatham, C.; Pouliot, M.; Authier, S. 2019: Non-human primate neuropharmacology refinement: Polysomnography and regional qEEG with social housing in ETS 123 compliant cages. Journal of Pharmacological and Toxicological Methods 99: 106595
Youngblood, B.L.; LaRose, A.; Geist, B.; Ueyama, Y.; Keller, A.; Muir, W.; Hamlin, R.; Wasielewski, R. 2019: Myocardial infarction model in a sheep. Journal of Pharmacological and Toxicological Methods 99: 106595
Espinel-Cohen, D.; Ortiz-Rodriguez, N.; Vargas-Pinto, P. 2019: Six-minute walk test does not affect blood pressure in healthy dogs at high altitude. Journal of Pharmacological and Toxicological Methods 99: 106595
Ueyama, Y.; Del Rio, C.; Palmieri, M.; Geist, B.; Hamlin, R. 2019: Evaluation of left ventricular function with continuous echocardiography concomitant with left ventricular pressure measurement in isoflurane anesthetized rats for safety pharmacology study. Journal of Pharmacological and Toxicological Methods 99: 106595
Sanders, K.M.; Gayheart-Walsten, P.; Speece, T.; Atterson, P.; Love, S. 2019: Core body temperature correction of QT interval in non-human primates. Journal of Pharmacological and Toxicological Methods 99: 106595
Didier, Hélène.; Salvetat, Céline.; Guilbot, Séphanie.; Rytved, K.A.; Printemps, R.; Le Grand, M. 2019: Effects of temperature changes on left ventricular cardiac functions and cardiac electrical activity parameters of guinea-pig isolated perfused heart. Journal of Pharmacological and Toxicological Methods 99: 106595
Petrella, C.; Wisialowski, T.; Bhatt, S. 2019: Left ventricular function assessment in rat cardiovascular telemetry studies and cross species comparison of drug-induced effects in dog. Journal of Pharmacological and Toxicological Methods 99: 106595
Okai, Y.; Matsune, K.; Shinozawa, T. 2019: Noninvasive system using human iPSC-derived cardiomyocytes to assess drug-induced inotropic changes. Journal of Pharmacological and Toxicological Methods 99: 106595
Millard, D.C.; Hayes, H.B.; Chvatal, S.A.; Nicolini, A.M.; Arrowood, C.A.; Clemens, M.; Ross, J.D. 2019: Multiwell microelectrode array technology for multimodal characterization of neural and cardiac networks in vitro. Journal of Pharmacological and Toxicological Methods 99: 106595
Gharanei, M.; Linekar, A.; Chuizbaian, O.; Wallis, R.; Maddock, H. 2019: Physiological work-loop contractions using isolated myocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Fletcher, S.; James, R.; Wallis, R.; Maddock, H.; Gharanei, M. 2019: The cardiac work-loop technique to assess drug-induced changes in cardiac contractility. Journal of Pharmacological and Toxicological Methods 99: 106595
LaRose, A.; Geist, G.E.; Ueyama, Y.; Palmieri, M.; Youngblood, B.L.; Mandic-Nowac, M.; Fronk, D.; Del Rio, C.; Hamlin, R. 2019: Acute hemodynamic and electrocardiographic changes during coronary embolization in a canine model. Journal of Pharmacological and Toxicological Methods 99: 106595
Vinci, T.; Ganzer, P.; Fetzek, C.; Hamlin, R.; Muir, W.; Zmarowski, A.; Hanjora, K.; Bresler, H.; Hawk, M.A. 2019: Non-invasive bioelectronic medicines for treating cardiopulmonary disease. Journal of Pharmacological and Toxicological Methods 99: 106595
Graziano, M.P.; Feric, N.; Sobbi-Aschar, R.; Pallotta, I.; Ushio, M. 2019: Biowire™ II human engineered cardiac tissues have clinically-relevant responses to inotropic agents as measured by the Cardiotype.Fo Assay. Journal of Pharmacological and Toxicological Methods 99: 106595
Geist, B.; LaRose, A.; Ueyama, Y.; Youngblood, B.L.; Palmieri, M.; Del Rio, C.; Hamlin, R. 2019: Serial coronary microembolization induced ischemic cardiomyopathy: Model refinement in the closed-chest Beagle dog. Journal of Pharmacological and Toxicological Methods 99: 106595
Boulay, E.; Menard, A.; Tan, W.; Dubuc-Mageau, M.; Sanfacon, A.; Pugsley, M.; Authier, S. 2019: Effects of common confounders on JTp and Tpe as novel proarrhythmia biomarkers. Journal of Pharmacological and Toxicological Methods 99: 106595
Arthur, S.R.; Love, A.; Bounous, D.I.; Ehrmann, J.; Lehman, B.; Johnson, W.; Smith, R.; Adamo, R.; Gill, M.; Hennan, J. 2019: Characterization of a renal hypertensive model in telemetrized cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods 99: 106595
Fitzgerald, K.; Morissette, P.; Chen, L.; Bueters, T.; Chaves, A.; Regan, C.; Sannajust, F. 2019: Characterization of a conscious, restrained, rabbit CV telemetry model for assessing hemodynamic and ECG risk liabilities in early drug research and development. Journal of Pharmacological and Toxicological Methods 99: 106595
Fanelli, P.; Regan, C.; Sannajust, F. 2019: Development of a semi-automated method to determine the amplitude of the ECG ST-segment to provide refined assessment of preclinical cardiovascular risk. Journal of Pharmacological and Toxicological Methods 99: 106595
Udupa, V.; Champéroux, P.; Richard, S.; Judé, S. 2019: Arrhythmic properties of valdecoxib in ischemia/reperfusion model in guinea pigs. Journal of Pharmacological and Toxicological Methods 99: 106595
Brockway, B.; Liddie, S.; Moddrelle, D.; Morton, X.; Delahanty, T.; Hamlin, R. 2019: Discrimination of the effects of three cardiac ion channel blockers using ECG biomarkers and arrhythmia incidence in St. Kitts green monkeys (Chlorocebus Sabaeus). Journal of Pharmacological and Toxicological Methods 99: 106595
Le Quément, C.; Mahler, S.; Lartigue, T.; Boissel, Séphanie.; De Macedo, M.; Loiseau, M.; Baudy, S.; Maurin, A.; La Rochelle, C.Drieu. 2019: Added value of echocardiography in telemetry studies: A non-invasive method for the assessment of drug-induced decrease in cardiac contractility in conscious dogs. Journal of Pharmacological and Toxicological Methods 99: 106595
Boucheix, O.; Bory, C.; Baudet, S. 2019: Investigation of orthostatic hypotension in conscious dogs within the context of regulatory toxicology studies. Journal of Pharmacological and Toxicological Methods 99: 106595
Baublits, J.T.; Barreda, J.; Engwall, M.J.; Vargas, H.; Chui, R. 2019: Leveraging machine learning for automated ECG and hemodynamic analyses in the anesthetized canine model. Journal of Pharmacological and Toxicological Methods 99: 106595
Baublits, J.T.; Sutherland, W.; Escamilla, M.; Barry, S.; Chui, R.; Engwall, M.J.; Vargas, H. 2019: Baseline characterization of three canine cardiovascular models. Journal of Pharmacological and Toxicological Methods 99: 106595
Takahashi, K.; Chujo, K.; Kanda, Y.; Sato, K. 2019: Characterization of neural networks of human induced pluripotent stem cell-derived neurons-Report from iPS non-clinical experiments for nervous system (iNCENS) project in collaboration with CSAHi and HESI NeuTox. Journal of Pharmacological and Toxicological Methods 99: 106595
Miyamoto, N.; Ojima, A.; Inaba, S.; Kitamura, T.; Osada, T.; Yoshinaga, T. 2019: Trial to detect significant metrics for drug-induced seizure liability using microelectrode arrays data analysis and primary rodent neurons: From multi-site pilot study of the HESI NeuTox consortium in collaboration with CSAHi and iNCENS. Journal of Pharmacological and Toxicological Methods 99: 106595
Millard, D.C.; Nicolini, A.M.; Arrowood, C.A.; Hayes, H.B.; Bradley, J.A.; Strock, C.J.; Freudenrich, T.M.; Wallace, K.; Shafer, T.J.; Cato, M.J.; Chaudhary, K.W.; Saavedra, L.; Haag, D.; Feaster, T.K.; Anson, B.D.; Luerman, G.; Hess, D.; Shi, Y.; Li, J.; Shi, H.; Levesque, P.; Kreir, M.; Lu, H.Rong.; Suzuki, I.; Odawara, A.; Miyamoto, N.; Ojima, A.; Kanda, Y.; Blinova, K.; Herr, D.; Roberts, R.; Pierson, J. 2019: Evaluating the use of microelectrode array technology and cell-based neuronal culture models for proconvulsant risk assessment: progress from the HESI NeuTox consortium. Journal of Pharmacological and Toxicological Methods 99: 106595
Rafi, K.; Hussain, S.Saad.; Faiza, S.; Simjee, S.U. 2019: Targeting neuroinflammation in Alzheimer's disease: An attractive strategy for the development of novel therapeutic approaches. Journal of Pharmacological and Toxicological Methods 99: 106595
Shahid, M.; Perveen, H.; Anjum, S.; Rizvi, N.S.; Simjee, S.U. 2019: AC-31B (essential oil) from Allium cepa regulate the expression of CD44 cell surface marker in PTZ-induced epileptic mice brain: A target to control epileptogenesis. Journal of Pharmacological and Toxicological Methods 99: 106595
Hess, D.; Fleming, C.; Palm, T.; Luerman, G. 2019: High-throughput (in vitro) phenotypic and seizure profiling using matured neuro-astrocyte co-cultures. Journal of Pharmacological and Toxicological Methods 99: 106595
Valentine, P.A.; Chaudhary, K.W.; Bahinski, A.; Talecki, L.J.; Kennis, B.; Anderson, W.A. 2019: Characterization of sodium channel blockade using inducible pluripotent stem cell-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Valentine, P.A.; Bahinski, A.; Petrucci, D.; Chaudhary, K.W.; Wilk, D.Dalmas.; Talecki, L.J. 2019: In vitro methods for detecting drug-induced hERG trafficking deficiencies. Journal of Pharmacological and Toxicological Methods 99: 106595
Okeyo, G.; Haedo, R.; Barthmes, M.; Bazzone, A.; Brüggemann, A.; George, M.; Stoelzle-Feix, S.; Fertig, N. 2019: A sensor based technique for pharmacological safety testing of cardiac transport proteins NCX, NaKATPase and respiratory chain complexes. Journal of Pharmacological and Toxicological Methods 99: 106595
Stoelzle-Feix, S.; Becker, N.; Obergrussberger, A.; de Boer, T.; Goversen, B.; van Veen, T.A.; Fertig, N. 2019: Introducing simulated IK1 into human iPSC-cardiomyocytes using dynamic clamp on an automated patch clamp system. Journal of Pharmacological and Toxicological Methods 99: 106595
McGlynn, K.; Firth, K.; MacQuaide, N.; Smith, G. 2019: Comparison of the effects of omecamtiv mercabil on excitation contraction coupling between isolated rabbit ventricular myocytes and human iPSC-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Palmer, J.A.; Smith, A.; Colwell, M.; Ludwig, M.; Gryshkova, V.; Valentin, J-Pierre.; Donley, E.; Kirchner, F.; Burrier, R. 2019: Prediction of cardiotoxicity potential using targeted metabolomics and human induced pluripotent stem cell-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Smith, G.; MacQuaide, N.; Nichols, J. 2019: Allowance for diastolic interval distinguishes Na channel block in iPSC-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Shi, H.; Huang, M.; Kwagh, J.; Levesque, P. 2019: Comparative electrophysiology and pharmacology of hiPSC cardiomyocyte 2D mono-cultures and 2D co-cultures with human ventricular fibroblasts. Journal of Pharmacological and Toxicological Methods 99: 106595
Obejero-Paz, C.A.; Wolford, R.; Bruening-Wright, A. 2019: Metabolic regulation of the electrophysiology and contractility of induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM). Journal of Pharmacological and Toxicological Methods 99: 106595
Wolters, B.; Doornbos, M.; Fleming, C.; Kettenhofen, R. 2019: Channelrhodopsin-2 transfected hiPSC-CMS allows for LED excitation/pacing on two MEA platforms. Journal of Pharmacological and Toxicological Methods 99: 106595
Lindqvist, A. 2019: Estimating hERG drug binding using temperature-controlled high-throughput automated patch-clamp. Journal of Pharmacological and Toxicological Methods 99: 106595
Lei, C.Lok.; Clerx, M.; Gavaghan, D.J.; Polonchuk, L.; Wang, K.; Mirams, G.R. 2019: High-throughput measurement and modeling of hERG kinetics using an automated platform. Journal of Pharmacological and Toxicological Methods 99: 106595
Lee, H-Ae.; Kim, K-Suk. 2019: Effects of antidepressants on cardiac multiple ion channels and action potentials in human iPS cell-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 99: 106595
Fisher, J.; Wu, C.; Liu, Z.; Kuryshev, Y.A.; Obejero-Paz, C.A.; Kramer, J.; Uffman, K.; Ostroski, R. 2019: Potency of Late-Nav1.5 current inhibition depends on the agonist used to augment it. Journal of Pharmacological and Toxicological Methods 99: 106595
Renganathan, M.; Koci, B.J.; Cook, A.; Wei, H.; Werth, D. 2019: Automated high-throughput Na + late current assay in QPatch HT platform for CiPA28. Journal of Pharmacological and Toxicological Methods 99: 106595
Koci, B.J.; Renganathan, M.; Cook, A.; Wei, H.; Werth, D. 2019: Optimization of cardiac CiPA targets (hCav1.2 and hKCNQ1/hminK) on the QPatch HT automated system. Journal of Pharmacological and Toxicological Methods 99: 106595
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Guo, D.; Sun, S.; Jenkinson, S. 2019: Simultaneous measurement of cardiac NAV1.5 peak and late currents in an automated QPatch platform. Journal of Pharmacological and Toxicological Methods 99: 106595
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Tse, K.; Hammar, O.; Ehrhardt, B. 2019: Making decisions on subjective data: Aligning statistics with science to improve outcomes on the modified Irwin test. Journal of Pharmacological and Toxicological Methods 99: 106595
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Rowton, S.; Ashcroft-Hawley, K.; Rocha, B. 2019: A data analysis strategy for regulatory rodent self-administration studies. Journal of Pharmacological and Toxicological Methods 99: 106595
Rowton, S.; Daroszewski, M. 2019: Induction of behavioral sensitisation in CD-1 mice: Cocaine and morphine dose regime effects. Journal of Pharmacological and Toxicological Methods 99: 106595
Rowton, S.; Tomczynski, S. 2019: Self-administration of diamorphine in male lister hooded rats. Journal of Pharmacological and Toxicological Methods 99: 106595
Mishra, R. 2019: Pharmacological investigation of biochemical and behavioral effects resembling Huntington's disease utilizing selective calcium and calmodulin dependent phosphodiesterase inhibitor. Journal of Pharmacological and Toxicological Methods 99: 106595
McMahon, L.R.; Hiranita, T.; Wilkerson, J.L.; Oyala, J.Francisco.Leon.; McCurdy, C.R. 2019: Pharmacological characterization of mitragynine, the primary constituent in Kratom, as a potential medication for opioid use disorder. Journal of Pharmacological and Toxicological Methods 99: 106595
Jackson, S.; Milne, A. 2019: Results of a survey on the use of the functional observational battery (FOB) and Irwin tests in central nervous system (CNS) safety pharmacology. Journal of Pharmacological and Toxicological Methods 99: 106595
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Smith, S.; Hallam, M.; Heal, D. 2019: An investigation of the reinforcing effects of MDMA in rats trained to self-administer heroin. Journal of Pharmacological and Toxicological Methods 99: 106595
Heal, D.; Kulkarni, R.; Pinder, L.; Rowley, H. 2019: Use of in vivo intracerebral microdialysis in rats to identify stimulant drugs of abuse. Journal of Pharmacological and Toxicological Methods 99: 106595
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Grochla, M.; Saucha, W.; Ciesla, D.; Knapik, P. 2020: Readmissions to General ICUs in a Geographic Area of Poland Are Seemingly Associated with Better Outcomes. International Journal of Environmental Research and Public Health 17(2)
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Maffi, L.; Paganini, M.; Vezzani, G.; Soumelis, A.; Aspati Research Group; Camporesi, E.M.; Bosco, G. 2020: Hyperbaric Oxygen Treatment for Carbon Monoxide Poisoning in Italy: Retrospective Validation of a Data Collection Tool for the Italian Registry of Carbon Monoxide Poisonings (IRCOP). International Journal of Environmental Research and Public Health 17(2)
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Oddone, E.; Bollon, J.; Nava, C.R.; Bugani, M.; Consonni, D.; Marinaccio, A.; Magnani, C.; Barone-Adesi, F. 2020: Predictions of Mortality from Pleural Mesothelioma in Italy After the Ban of Asbestos use. International Journal of Environmental Research and Public Health 17(2)
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