EurekaMag
+ Translate
+ Most Popular
Gaucher's disease;thirty-two years experience at Siriraj Hospital
A study of Macrobathra Meyrick from China (Lepidoptera, Cosmopterigidae)
First occurrence in ores of tetragonal chalcocite
Effects of trace element nutrition on sleep patterns in adult women
N.Z. range management guidelines. 2. Design of grazing management systems for tussock country
A case of lipoma of the esophagus
A revision of world Acanthosomatidae (Heteroptera: Pentatomidae): keys to and descriptions of subfamilies, tribes and genera, with designation of types
Life history of the coronate scyphozoan Linuche unguiculata (Swartz, 1788)
Perceptual restoration of obliterated sounds
Mutagenicity studies on two chromium(III) coordination compounds
The formation of the skeleton. I. Growth of a long bone. 1st appearance of a center of calcification
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis
The joint commission: four key root causes loom large in sentinel event data
Treatment of vitiligo with topical 15% lactic acid solution in combination with ultra violet-A
Behaviour of dairy cows within three hours after feed supply: I. Influence of housing type and time elapsing after feed supply
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Management and control of patients with type 2 diabetes mellitus in Lebanon: results from the International Diabetes Management Practices Study (IDMPS)
The diet composition and nutritional knowledge of patients with anorexia nervosa
Physoporella croatica Herak, 1958 of the Slovak karst Anisian (Slovakia, the West Carpathians Mts.)
Bright lights, big noise. How effective are vehicle warning systems?
Ein Plesiosaurier-Rest mit Magensteinen aus mittlerem Lias von Quedlinburg
Incidence of Chlamydia trachomatis in patients with sterility
Monster soup: the microscope and Victorian fantasy
Preliminary tests with residual sprays against poultry lice
Duration of the life of plants in phylogeny

Framework for Drug Formulary Decision Using Multiple-Criteria Decision Analysis


Framework for Drug Formulary Decision Using Multiple-Criteria Decision Analysis



Medical Decision Making: An International Journal of the Society for Medical Decision Making 40(4): 438-447



ISSN/ISBN: 0272-989X

PMID: 32338143

DOI: 10.1177/0272989x20915241

Background. Reviewing drugs to determine coverage or reimbursement level is a complex process that involves significant time and expertise. Review boards gather evidence from the submission provided, input from clinicians and patients, and results of clinical and economic reviews. This information consists of assessments on multiple criteria that often conflict with one another. Multiple-criteria decision analysis (MCDA) includes methods to address complex decision making problems with conflicting objectives and criteria. We propose an MCDA approach that infers a utility model based on reviews of previously submitted drugs. Methods. We use a recent extension of the UTilitiés Additives DIScriminantes approach, UTADISGMS. This disaggregation approach deconstructs a portfolio of elements such as a set of drugs that have been reviewed and for which a decision has been made. It derives global and marginal utility functions that are consistent with the preferences exhibited by the review boards in their recommendations. We apply the method to oncology drugs reviewed in Canada between 2011 and 2017. We also illustrate how to conduct scenario analyses and predict the coverage decisions for new drugs. Results. Applying the method yields a utility value for each submission along with a set of thresholds that partition the utility values based on the submission outcomes. Scenario analyses illustrate the predictive ability of the method. Conclusion. Preference disaggregation is an indirect way of eliciting an additive global utility value function. It requires less of a cognitive effort from the decision making bodies because it infers preferences from the data rather than relying on direct assessments of model parameters. We illustrate how it can be applied to validate existing decisions and to predict the recommendation of a new drug.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 070061915

Download citation: RISBibTeXText

Related references

Development and Practical Application of a Multiple-Criteria Decision Analysis Framework on Respiratory Inhalers: Is It Always Useful in the MOH Malaysia Medicines Formulary Listing Context?. Mdm Policy and Practice 6(1): 2381468321994063, 2021

Op58 Testing of a Multiple Criteria Decision Analysis Value Framework with Decision Makers Across Europe. International Journal of Technology Assessment in Health Care 33(S1): 25-26, 2017

Drug Evaluation and Decision Making in Catalonia: Development and Validation of a Methodological Framework Based on Multi-Criteria Decision Analysis (Mcda) for Orphan Drugs. International Journal of Technology Assessment in Health Care 33(1): 111-120, 2017

Integrating multiple criteria decision making models into the decision support system framework for marketing decisions. Naval Research Logistics 35(6): 575-596, 1988

Development of the WHO-INTEGRATE evidence-to-decision framework: an overview of systematic reviews of decision criteria for health decision-making. Cost Effectiveness and Resource Allocation: C/E 18: 8, 2020

Development of multi-criteria decision analysis (MCDA) framework for off-patent pharmaceuticals - an application on improving tender decision making in Indonesia. Bmc Health Services Research 18(1): 1003, 2018

Multiple Criteria Decision Analysis for HTA across four EU Member States: Piloting the Advance Value Framework. Social Science and Medicine 246: 112595, 2020

A DSS for multiple criteria decision analysis with imprecisely specified trade-offs : Multicriteria decision support. European Journal of Operational Research 113(2): 261-270, 1999

A Multiple-Criteria Decision Analysis Framework for Developing and Evaluating Coastal Retreat Policy. Integrated Environmental Assessment and Management 2022, 2022

Utilization of multiple-criteria decision analysis (MCDA) to support healthcare decision-making FIFARMA, 2016. Journal of Market Access and Health Policy 5(1): 1360545, 2017

Value-based decision-making for orphan drugs with multiple criteria decision analysis: burosumab for the treatment of X-linked hypophosphatemia. Current Medical Research and Opinion 2021: 1, 2021

Patient decision aid based on multi-criteria decision analysis for disease-modifying drugs for multiple sclerosis: prototype development. Bmc Medical Informatics and Decision Making 21(1): 123, 2021

Multiple Criteria Decision Analysis (MCDA) for evaluating new medicines in Health Technology Assessment and beyond: The Advance Value Framework. Social Science and Medicine 188: 137-156, 2017

Multi-Criteria Decision Analysis as a Decision-Support Tool for Drug Evaluation: a Pilot Study in a Pharmacy and Therapeutics Committee Setting. International Journal of Technology Assessment in Health Care 34(5): 519-526, 2018

Can multi-criteria decision analysis (MCDA) be implemented into real-world drug decision-making processes? A Canadian provincial experience. International Journal of Technology Assessment in Health Care 2020: 1-6, 2020