Active-site-specific zinc-depleted and reconstituted cobalt (Ii) human-liver alcohol dehydrogenase : Preparation, characterization and complexation with Nadh and trans -4- ( N, N -dimethylamino) -cinnamaldehyde
Coimbra, Joao Carlos; Pinto, Iraja Damiani; Wurdig, Norma Luiza; Do Carmo, Dermeval Aparecido
FEBS Journal 173(2): 275-280
1988
ISSN/ISBN: 1742-464X
DOI: 10.1111/j.1432-1033.1988.tb13995.x
Accession: 070206997
PDF emailed within 0-6 h: $19.90
Related References
Schneider-Bernlöhr, H.; Formicka-Kozłowska, G.; Bühler, R.; von Wartburg, J.P.; Zeppezauer, M. 1988: Active-site-specific zinc-depleted and reconstituted cobalt(II) human-liver alcohol dehydrogenase. Preparation, characterization and complexation with NADH and trans-4-(N,N-dimethylamino)-cinnamaldehyde European Journal of Biochemistry 173(2): 275-280Dietrich, H.; Maret, W.; Wallén, L.; Zeppezauer, M. 1979: Active-site-specific reconstituted cobalt(II) horse-liver alcohol dehydrogenase. Changes of the spectra of the substrate trans-4-(N,N-dimethylamino)-cinnamaldehyde and of the catalytic cobalt ion upon ternary complex formation with NADH and 1,4,5,6-tetrahydronicotinamide--adenine dinucleotide European Journal of Biochemistry 100(1): 267-270
Piersma, S.R.; Norin, A.; de Vries, S.; Jörnvall, H.; Duine, J.A. 2003: Inhibition of nicotinoprotein (NAD+-containing) alcohol dehydrogenase by trans-4-(N,N-dimethylamino)-cinnamaldehyde binding to the active site Journal of Protein Chemistry 22(5): 457-461
Schneider, G.; Eklund, H.; Cedergren-Zeppezauer, E.; Zeppezauer, M. 1983: Structure of the complex of active site metal depleted horse liver alcohol dehydrogenase ec 1.1.1.1 and nadh EMBO (European Molecular Biology Organization) Journal 2(5): 685-690
Schneider, G.; Eklund, H.; Cedergren-Zeppezauer, E.; Zeppezauer, M. 1983: Structure of the complex of active site metal-depleted horse liver alcohol dehydrogenase and Nadh The Embo Journal 2(5): 685-689
Schneider, G.; Eklund, H.; Cedergren-Zeppezauer, E.; Zeppezauer, M. 1983: Structure of the complex of active site metal-depleted horse liver alcohol dehydrogenase and NADH EMBO Journal 2(5): 685-689
Dahl, K.H.; Dunn, M.F. 1984: Reaction of 4-trans-(N,N-dimethylamino)cinnamaldehyde with the liver alcohol dehydrogenase-oxidized nicotinamide adenine dinucleotide complex Biochemistry 23(18): 4094-4100
Schneider, G.; Zeppezauer, M. 1983: Kinetics and mechanisms of the recombination of zinc ii cobalt ii and nickel ii with the metal depleted catalytic site of horse liver alcohol dehydrogenase ec 1.1.1.1 Journal of Inorganic Biochemistry 18(1): 59-70
Schneider, G.; Cedergren-Zeppezauer, E.; Knight, S.; Eklund, H.; Zeppezauer, M. 1985: Active site specific cadmium(II)-substituted horse liver alcohol dehydrogenase: crystal structures of the free enzyme, its binary complex with NADH, and the ternary complex with NADH and bound p-bromobenzyl alcohol Biochemistry 24(25): 7503-7510
Schneider, G.; Eklund, H.; Cedergren-Zeppezauer, E.; Zeppezauer, M. 1983: Crystal structures of the active site in specifically metal-depleted and cobalt-substituted horse liver alcohol dehydrogenase derivatives Proceedings of the National Academy of Sciences of the United States of America 80(17): 5289-5293
Cedergren-Zeppezauer, E.; Samama, J.P.; Eklund, H. 1982: Crystal structure determinations of coenzyme analogue and substrate complexes of liver alcohol dehydrogenase: binding of 1,4,5,6-tetrahydronicotinamide adenine dinucleotide and trans-4-(N,N-dimethylamino)cinnamaldehyde to the enzyme Biochemistry 21(20): 4895-4908
Morris, R.G.; Saliman, G.; Dunn, M.F. 1980: Evidence that hydride transfer precedes proton transfer in the liver alcohol dehydrogenase catalyzed reduction of trans-4-(N,N-dimethylamino)cinnamaldehyde Biochemistry 19(4): 725-731
Maret, W.; Dietrich, H.; Ruf, H.H.; Zeppezauer, M. 1980: Active site-specific reconstituted copper(II) horse liver alcohol dehydrogenase: a biological model for type 1 Cu2+ and its changes upon ligand binding and conformational transitions Journal of Inorganic Biochemistry 12(3): 241-252
Dunn, M.F.; Dietrich, H.; MacGibbon, A.K.; Koerber, S.C.; Zeppezauer, M. 1982: Investigation of intermediates and transition states in the catalytic mechanisms of active site substituted cobalt(II), nickel(II), zinc(II), and cadmium(II) horse liver alcohol dehydrogenase Biochemistry 21(2): 354-363
Sartorius, C.; Gerber, M.; Zeppezauer, M.; Dunn, M.F. 1987: Active-site cobalt(II)-substituted horse liver alcohol dehydrogenase: characterization of intermediates in the oxidation and reduction processes as a function of pH Biochemistry 26(3): 871-882