Organocatalytic enantioselective aza-Friedel-Crafts reaction of sesamols with N-sulfonylimines 6 '-OH Cinchona alkaloids
Chauhan, P.; Chimni, S.S.
Tetrahedron Letters 54(35): 4613-4616
ISSN/ISBN: 0040-4039 DOI: 10.1016/j.tetlet.2013.06.032
An unprecedented asymmetric aza-Friedel-Crafts reaction of sesamol with N-sulfonylimines has been reported. A variety of N-sulfonylimines reacts with sesamol derivatives in the presence of 6'-OH Cinchona alkaloids to provide a new series of chiral aminophenol adducts in good yield and good to high level of enantioselectivity. rights reserved.