Case fatality of COVID-19 in patients with neurodegenerative dementia
Reyes-Bueno, J.A.; Mena-Vázquez, N.; Ojea-Ortega, T.; Gonzalez-Sotomayor, M.M.; Cabezudo-Garcia, P.; Ciano-Petersen, N.L.; Pons-Pons, G.; Castro-Sánchez, M.V.; Serrano-Castro, P.J.
Neurologia 35(9): 639-645
The elderly population is the group most threatened by COVID-19, with the highest mortality rates. This study aims to analyse the case fatality of COVID-19 in a cohort of patients with degenerative dementia. We conducted a descriptive case-control study of a sample of patients diagnosed with primary neurodegenerative dementia. Twenty-four of the 88 patients with COVID-19 included in the study died: 10/23 (43.4%) patients diagnosed with dementia and 14/65 (21.5%) controls; this difference was statistically significant. Our results suggest that case fatality of COVID-19 is significantly higher among patients with primary degenerative dementia than in other patients with similar mean ages and comorbidities.