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Live mammalian cell arrays

Live mammalian cell arrays

Nature Methods 10(6): 550-552

ISSN/ISBN: 1548-7091

PMID: 23644546

DOI: 10.1038/nmeth.2473

High-content assays have the potential to drastically increase throughput in cell biology and drug discovery, but handling and culturing large libraries of cells such as primary tumor or cancer cell lines requires expensive, dedicated robotic equipment. We developed a simple yet powerful method that uses contact spotting to generate high-density nanowell arrays of live mammalian cells for the culture and interrogation of cell libraries.

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Accession: 072055066

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