Seropositivity and risk factors of Toxocara canis infection in adult asthmatic patients
Rouhani-Rankouhi, S.Z.; Kow, K.S.; Liam, C.K.; Lau, Y.L.
Tropical Biomedicine 37(3): 599-608
2020
ISSN/ISBN: 2521-9855
PMID: 33612775
Accession: 072519859
This cross-sectional study involving 86 adult asthmatic patients aimed to determine the relationship between Toxocara seropositivity and severity of asthma in adult asthmatics and investigate the risk factors for Toxocara infection. In all cases, T. canis IgG level was measured using an anti-Toxocara IgG enzyme-linked immunosorbent assay kit. Total serum IgE and eosinophil count were also determined. The anti-Toxocara IgG seropositivity was 68.6% among asthmatic patients. There were no statistically significant associations between Toxocara seroprevalence and other risk factors, clinical symptoms of asthma and high level of total serum IgE and eosinophilia. Pet ownership could be an important risk factor for Toxocariasis. Having a pet at home and wheezing were significantly associated with Toxocara seropositivity in adult asthmatic patients.