Photodynamic cell injury in the red and IR-absorption bands of endogenous oxygen

Danilov, V.P.; Zakharov, S.D.; Ivanov, A.V.; Murina, T.M.; Eremeev, B.V.; Mashalov, A.A.; Novkov, E.G.; Panasenko, N.A.; Perov, S.N.; Prokhorov, A.M.; Danilov, V.P; Zakharov, S.D; Ivanov, A.V; Murina, T.M; Eremeev, B.V; Mashalov, A.A; Novkov, E.G; Panasenko, N.A; Perov, S.N; Prokhorov, A.M

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Photodynamic cell injury in the red and IR-absorption bands of endogenous oxygen

Danilov, V.P.; Zakharov, S.D.; Ivanov, A.V.; Murina, T.M.; Eremeev, B.V.; Mashalov, A.A.; Novkov, E.G.; Panasenko, N.A.; Perov, S.N.; Prokhorov, A.M.

Doklady Akademii Nauk SSSR 311(5): 1255-1258

1990

ISSN/ISBN: 0002-3264

PMID: 2209393

Accession: 007653328

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Summary

The experiments were conducted with human erythrocytes and with mice with transplantable solid Lewis sarcoma. Cell injuries during irradiation in O2 absorption bands due to direct photoexcitation are similar to the results of usual photodynamic effects. In principle, phototherapy without exogenous photsensitizers is possible, when irradiation is conducted in the O2 absorption band. This phototherapy is not toxic, and oxygen-exciting radiation in the nearest IR bands corresponds to the maximal transparency window of biotissues.