A quantitative modification of the complement fixation test applied to the study of the sequence of inclusion of different organs in immunogenesis

Prokopenko, L.G.; Evnin, D.N.; Prokopenko, L.G; Evnin, D.N

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A quantitative modification of the complement fixation test applied to the study of the sequence of inclusion of different organs in immunogenesis

Prokopenko, L.G.; Evnin, D.N.

Zh Mikrobiol Epidemiol Immunobiol 42(5): 143-145

1965

Accession: 024188459

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Summary

With the aid of the complement fixation reaction (by 50 per cent titre) it was shown that following primary immunization the greatest amount of antibodies accumulated in the blood serum and much less -in the lungs and spleen; the antibodies were the last to appear in the liver. Electrophoretic motility of the antibodies synthesized in the liver differed from that of the antibodies formed in the spleen and lungs. Distribution of antibodies in passively immunized animals differed from that in the actively immunized animals.