Usefulness of taurine in chronic congestive heart failure and its prospective application

Azuma, J.; Sawamura, A.; Awata, N.; Azuma, J; Sawamura, A; Awata, N

doi:10.1253/jcj.56.95

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Usefulness of taurine in chronic congestive heart failure and its prospective application

Azuma, J.; Sawamura, A.; Awata, N.

Japanese Circulation Journal 56(1): 95-99

1992

ISSN/ISBN: 0047-1828

PMID: 1538580

DOI: 10.1253/jcj.56.95
Accession: 034161926

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Summary

We compared the effect of oral administration of taurine (3 g/day) and coenzyme Q10 (CoQ10) (30 mg/day) in 17 patients with congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy, whose ejection fraction assessed by echocardiography was less than 50%. The changes in echocardiographic parameters produced by 6 weeks of treatment were evaluated in a double-blind fashion. In the taurine-treated group significant treatment effect was observed on systolic left ventricular function after 6 weeks. Such an effect was not observed in the CoQ10-treated group.

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