Top Buy Now Summary References
Home
>
Section
>
Chapter

Diagnosis and treatment of chronic lead poisoning in CAPD patients

Kessler, M.; Durand, P.Y.; Hestin, D.; Gamberoni, J.; Chanliau, J.

Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis 9: 143-146

1993

ISSN/ISBN: 1197-8554
PMID: 8105909
Accession: 045768552

Full-Text Article emailed within 1 workday
Payments are secure & encrypted
Powered by Stripe
Powered by PayPal

Summary
In order to screen for abstruse lead poisoning in continuous ambulatory peritoneal dialysis (CAPD) patients, delta-aminolevulinic acid dehydratase (ALAD) levels were measured in 18 CAPD patients, 156 patients treated with hemodialysis (HD), and 420 control patients with normal renal function (NRF). An EDTA (ethylenediamine tetraacetic acid) mobilization test was performed in patients with low levels of ALAD (< 0.40 mumol of porphobilinogen formed per milliliter of red blood cells): 1 g of EDTA was infused IV followed by 20 L of hemofiltrate in HD patients and four bags of dialysate in CAPD patients. Lead was assayed in the ultrafiltrate liquid, the bags of dialysate, and in the 24-hour urine. ALAD levels were significantly lower in CAPD and HD patients than in the NRF subjects. ALAD was significantly correlated with EDTA mobilized lead in both dialysis and NRF patients. Using the usual criteria (EDTA mobilized lead > 800 micrograms/24 hours), the rate of lead poisoning observed was similar in the two groups. These results suggest that ALAD assay followed by the EDTA mobilization test is as effective in CAPD patients as in NRF subjects to diagnose and to treat chronic abstruse lead poisoning.

References

Du, X.; Zheng, W.; Ye, Q. 2020: Rare cases of severe life-threatening lead poisoning due to accident or chronic occupational exposure to lead and manganese: Diagnosis, treatment, and prognosis Toxicology and Industrial Health 36(12): 951-959
Gundersen, T.; Ibsen, T.; Johansen, S. 1982: Chronic lead poisoning occurrence diagnosis and treatment Tidsskrift for den Norske Laegeforening 102(14): 804-806, 811
Giuliano, G.; Marras, O.; Focardi, L.; Lampis, R. 1969: Peripapillary retinal pigmentation as an early sign of lead poisoning. Control findings in 53 subjects with chronic occupational lead poisoning or exposed to lead Annali di Ottalmologia E Clinica Oculistica 95(11): 913-920
Sánchez Sánchez, M.L.; Rubio Pérez, P.; Calvo Manuel, E.; Arroyo Vicente, M.; Millán Núñez-Cortés, J.; Espinos Pérez, D. 1979: Criteria in the diagnosis of lead poisoning. II. Lead levels in blood and urine corresponding to normal subjects and lead poisoning patients, in basal situations and after intravenous calcium EDTA administration Revista Clinica Espanola 153(3): 207-211
Kehoe, R.A.; Cholak, J.; Hubbard, D.M.; Bambach, K.; Mcnary, R.R. 1943: Experimental Studies on Lead Absorption and Excretion and their Relation to the Diagnosis and Treatment of Lead Poisoning J. industr. Hyg 25: 71-79
Herman, D'souza.Sunil.; Geraldine, M.; Venkatesh, T. 2007: Evaluation, diagnosis, and treatment of lead poisoning in a patient with occupational lead exposure: a case presentation Journal of Occupational Medicine and Toxicology 2: 7
Sánchez-Fructuoso, A.I.; Cano, M.; Arroyo, M.; Fernández, C.; Prats, D.; Barrientos, A. 2002: Lead mobilization during calcium disodium ethylenediaminetetraacetate chelation therapy in treatment of chronic lead poisoning American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation 40(1): 51-58
Bedereu, V.V. 1986: Problem in the diagnosis of chronic lead poisoning Zdravookhranenie (Kishinev) (6): 48-50
Herrera, J.M. 1956: Several histopathological observations on chronic lead poisoning; two fatal cases of collective poisoning with tetraethyl lead Archivos Medicos Panamenos 5(1): 8-23
Kelentey, B.; Szazados, I.; Takacs, I.; Halmai, Z.; Valyi-Nagy, T. 1957: Studies on experimental lead poisoning. IV. Metabolism of rats at rest and under exercise in chronic lead poisoning Acta Physiologica Academiae Scientiarum Hungaricae 12(1-3): 277-281
Corrigan, C.E. 1967: Fallacies in the diagnosis of chronic lead poisoning in industry Manitoba Medical Review 47(10): 559-560
Valyi-Nagy, T.; Kocsar, L.; Kelentei, B.; Csernyanszky, H. 1954: Studies on experimental lead poisoning. I. Effects of alcohol-ingestion on chronic lead poisoning in the rat Acta Physiologica Academiae Scientiarum Hungaricae 5(3-4): 531-536
Urin, V.M.; Manchak, L.V.; Semenova, G.S. 1970: The diagnosis of the initial manifestations of chronic mercury and lead poisoning Faktory Vneshnikh Sred Znachenie Zdorov'ya Naseleniya Respublikanskii Mezhvedomstvennyi Sbornik 2: 150-152
Burgat, V.; Pinault, L.; Cabrit, M.; Milhaud, G. 1995: Diagnosis and treatment of lead poisoning in the dog Recueil de Medecine Veterinaire de l'Ecole d'Alfort 171(2-3): 153-158
White, H.H. 1960: Diagnosis and treatment of lead poisoning World Neurology 1: 137-149
Thorsen, K. 1960: Diagnosis and treatment of lead poisoning Ugeskrift for Laeger 122: 975-979
Rasevskaja, A.M.; Voroncova, E.I. 1969: Early diagnosis, evaluation of work ability and prophylaxisim chronic lead poisoning Arhiv Za Higijenu Rada i Toksikologiju 20(4): 651-655
Klein, M.; Kaminsky, P.; Duc, M.L.; Duc, M. 1994: Current diagnosis and treatment of lead poisoning La Revue de Medecine Interne 15(2): 101-109
Batuman, V.; Wedeen, R.P.; Bogden, J.D.; Balestra, D.J.; Jones, K.; Schidlovsky, G. 1989: Reducing bone lead content by chelation treatment in chronic lead poisoning: an in vivo X-ray fluorescence and bone biopsy study Environmental Research 48(1): 70-75
De Bruin, J. 1967: Ca-DTPA in the treatment of chronic lead poisoning Nederlands Tijdschrift Voor Geneeskunde 111(18): 824-826