Diagnosis and treatment of endocrine disorders in the HIV-infected patient

Corcoran, C.P.; Grinspoon, S.; Corcoran, C.P; Grinspoon, S

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Diagnosis and treatment of endocrine disorders in the HIV-infected patient

Corcoran, C.P.; Grinspoon, S.

Journal of the International Association of Physicians in Aids Care 4(2): 10-14; 34

1998

ISSN/ISBN: 1081-454X

PMID: 11365082

Accession: 045768663

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Summary

Hormonal disturbances are common in patients with advanced HIV disease, and these imbalances may contribute to the loss of muscle and lean body mass. The most common endocrine manifestations related to HIV disease are reviewed and potential therapeutic strategies for combating AIDS wasting syndrome are discussed. Discussions include disturbances related to gonadal function and androgen levels, energy metabolism, growth hormone abnormalities, problems with adrenal and thyroid function, and disturbances in sodium and water balances. Disruptions in calcium, glucose, and lipid metabolism in AIDS patients are also examined. The anabolic agents nandrolone decanoate and oxandrolone are highlighted as therapies to AIDS wasting syndrome. While there are some benefits from these agents, both require further research to assess efficacy. Oral anabolic agents being studied include natural testosterone derivatives and growth hormone.

Diagnosis and treatment of endocrine disorders in the HIV-infected patient

Corcoran, C.P.; Grinspoon, S.

Journal of the International Association of Physicians in Aids Care 4(2): 10-14; 34

1998

Full-Text Article emailed within 1 workday

Summary

References