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Strategy for breast conserving treatment--analysis of recurrence and prognosis after breast cosnserving treatment

Shin, E.; Takatsuka, Y.; Okamura, Y.; Fukuda, K.; Mishima, H.; Tono, T.; Yagyu, T.; Kobayashi, K.; Kikkawa, N.; Takeda, M.; Kurata, A.; Otani, M.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 23(Suppl 1): 92-99

1996

ISSN/ISBN: 0385-0684
PMID: 8702319
Accession: 047446242

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Summary
Two hundred and four patients with small breast cancer (T < or = 3.0 cm. N0 or N1a) were given breast conserving treatment (radiation group: 101, non-radiation group: 103) during the period from Feb. 1988 to Jan. 1995. Survival analysis of breast conserving treatment radiation group versus non-radiation group revealed the following: 1) Breast conserving treatment had a good prognosis, and a 5-year overall survival rate of 96.2%. 2) There was no significant difference of 5-year overall, disease-free and ipsilateral breast disease-free survival rate between the radiation group and non-radiation group. 3) Surgical margin involvement was the most significant risk factor in local recurrence after breast conserving treatment, and non-radiation was a possible risk factor. 4) Local recurrence was a significant risk factor for distant metastases after breast conserving treatment the same as node positive. These results suggested as follows: 1) Lumpectomy with a clear margin and radiation is the best choice for small breast cancer (T < or = 3.0 cm, N0 or N1a). 2) Adjuvant therapy after surgical treatment is necessary for local recurrence.

References

Voogd, A.C.; Rodrigus, P.T.; Crommelin, M.A.; Repelaer van Driel, O.J.; Roukema, J.A.; Coebergh, J.W. 1995: Local recurrence following breast-conserving treatment for breast carcinoma; treatment and prognosis in 82 patients Nederlands Tijdschrift Voor Geneeskunde 139(47): 2422-2427
Van der Sangen, M.J.C.; Poortmans, P.M.P.; Scheepers, S.W.M.; Lemaire, B.M.D.; van Berlo, C.L.H.; Tjan-Heijnen, V.C.G.; Voogd, A.C. 2013: Prognosis following local recurrence after breast conserving treatment in young women with early breast cancer European Journal of Surgical Oncology: the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 39(8): 892-898
Verhoef, L.C.; Stalpers, L.J.; Verbeek, A.L.; Wobbes, T.; van Daal, W.A. 1991: Breast-conserving treatment or mastectomy in early breast cancer: a clinical decision analysis with special reference to the risk of local recurrence European Journal of Cancer 27(9): 1132-1137
Solin, L.J.; Fourquet, A.; Mccormick, B.; Haffty, B.; Recht, A.; Schultz, D.J.; Barrett, W.; Fowble, B.; Kuske, R. 1993: Salvage treatment for recurrence in the breast following breast-conserving surgery and definitive irradiation for ductal carcinoma in situ of the breast International Journal of Radiation Oncology Biology Physics 27(Suppl 1): 146
Dalberg, K.; Mattsson, A.; Sandelin, K.; Rutqvist, L.E. 1997: Outcome of treatment for ipsilateral breast tumor recurrence following breast-conserving surgery of early-stage breast cancer Breast Cancer Research and Treatment 46(1): 98
Walstra, C.J.E.F.; Schipper, R.-J.; van Riet, Y.E.; van der Toorn, P.-P.G.; Smidt, M.L.; Sangen, M.J.C.V.; Voogd, A.C.; Nieuwenhuijzen, G.A.P. 2021: Repeat breast-conserving treatment of ipsilateral breast cancer recurrence: a nationwide survey amongst breast surgeons and radiation oncologists in the Netherlands Breast Cancer Research and Treatment 187(2): 499-514
Wai, E; Solin, L; Fourquet, A; Vincini, F; Taylor, M; Haffty, B; Olivotto, I; Strom, E; Pierce, L; Marks, L 2004: Salvage treatment for local recurrence after breast-conserving surgery followed by radiation as initial treatment for mammographically-detected ductal carcinoma in situ of the breast International Journal of Radiation Oncology*biology*physics 60: S133-S133
Solin, L.J.; Fourquet, A.; Vicini, F.A.; Haffty, B.; Taylor, M.; McCormick, B.; McNeese, M.; Pierce, L.J.; Landmann, C.; Olivotto, I.A.; Borger, J.; de La Rochefordiere, A.; Schultz, D.J. 2001: Salvage treatment for local recurrence after breast-conserving surgery and radiation as initial treatment for mammographically detected ductal carcinoma in situ of the breast Cancer 91(6): 1090-1097
Komoike, Y.; Akiyama, F.; Iino, Y.; Ikeda, T.; Akashi-Tanaka, S.; Ohsumi, S.; Kusama, M.; Sano, M.; Shin, E.; Suemasu, K.; Sonoo, H.; Taguchi, T.; Nishi, T.; Nishimura, R.; Haga, S.; Mise, K.; Kinoshita, T.; Murakami, S.; Yoshimoto, M.; Tsukuma, H.; Inaji, H. 2006: Ipsilateral breast tumor recurrence (IBTR) after breast-conserving treatment for early breast cancer: risk factors and impact on distant metastases Cancer 106(1): 35-41
Anderson, S.J.; Wapnir, I.; Dignam, J.J.; Fisher, B.; Mamounas, E.P.; Jeong, J-Hyeon.; Geyer, C.E.; Wickerham, D.Lawrence.; Costantino, J.P.; Wolmark, N. 2009: Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in patients treated by breast-conserving therapy in five National Surgical Adjuvant Breast and Bowel Project protocols of node-negative breast cancer Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology 27(15): 2466-2473
Motwani, S.B.; Haffty, B.G. 2010: Prognosis After Ipsilateral Breast Tumor Recurrence and Locoregional Recurrences in Patients Treated by Breast-Conserving Therapy in Five National Surgical Adjuvant Breast and Bowel Project Protocols of Node-Negative Breast Cancer Breast Diseases: A Year Book Quarterly 21(3): 269-270
Van Tienhoven, G.; Voogd, A.C.; Peterse, J.L.; Nielsen, M.; Andersen, K.W.; Mignolet, F.; Sylvester, R.; Fentiman, I.S.; van der Schueren, E.; van Zijl, K.; Blichert-Toft, M.; Bartelink, H.; van Dongen, J.A. 1999: Prognosis after treatment for loco-regional recurrence after mastectomy or breast conserving therapy in two randomised trials (EORTC 10801 and DBCG-82TM). EORTC Breast Cancer Cooperative Group and the Danish Breast Cancer Cooperative Group European Journal of Cancer 35(1): 32-38
Ishitobi, M.; Komoike, Y.; Nakahara, S.; Motomura, K.; Koyama, H.; Inaji, H. 2011: Repeat lumpectomy for ipsilateral breast tumor recurrence after breast-conserving treatment Oncology 81(5-6): 381-386
Lawrence, J. Solin; Alain Fourquet; Beryl McCormick; Bruce Haffty; Abram Recht; Delray, J. Schultz; William Barrett; Barbara Fowble; Robert Kuske; Marie Taylor; Marsha McNeese; Robert Amalric; John Kurtz 1993: Salvage treatment for recurrence in the breast following breast-conserving surgery and definitive irradiation for ductal carcinoma in situ (intraductal carcinoma) of the breast International Journal of Radiation Oncology*biology*physics 27(Supp-S1): 146-147
Ofuchi, T.; Amemiya, A.; Hatayama, J. 2007: Salvage surgery for patients with ipsilateral breast tumor recurrence after breast-conserving treatment Nihon Rinsho. Japanese Journal of Clinical Medicine 65(Suppl 6): 439-444
Van Tienhoven, G.; Voogd, A.C.; Blicherttoft, M.; Bartelink, H.; Van Dongen, J.A.; Peterse, J.L.; Nielsen, M.; Andersen, K.W.; Mignolet, F.; Sylvester, R.; Fentiman, I.S.; Van der Schueren, E.; Van Zijl, K.; Eoortc, B.O.V.E.N. G. 1999: Prognosis after treatment for loco-regional recurrence after mastectomy or breast conserving therapy in two randomised trials (EORTC 10801 and DBCG-82TM) European Journal of Cancer (1990) 35(1): 32-38
Fourquet, A.; Dreyfus, H.; Colombani, H.; Maher, M.; Gozy, M.; Campana, F.; Vilcoq, J.R. 1995: Influence of surgery-radiotherapy interval on recurrence in breast-conserving treatment of small breast cancer International Journal of Radiation Oncology Biology Physics 32(Suppl 1): 260
Demicheli, R.; Ardoino, I.; Ambrogi, F.; Agresti, R.; Biganzoli, E. 2013: Significance of ipsilateral breast tumor recurrence after breast conserving treatment: role of surgical removal Chinese Journal of Cancer Research 25(1): 22-31
Noh, J.M.; Choi, D.H.; Huh, S.J.; Park, W.; Yang, J.H.; Nam, S.J.; Im, Y.H.; Ahn, J.S. 2011: Patterns of recurrence after breast-conserving treatment for early stage breast cancer by molecular subtype Journal of Breast Cancer 14(1): 46-51