Top Buy Now Summary References
Home
>
Section
>
Chapter

Postoperative Changes in Nutritional and Functional Status of Gastroesophageal Cancer Patients

Lidoriki, I.; Schizas, D.; Mylonas, K.S.; Vergadis, C.; Karydakis, L.; Alexandrou, A.; Karavokyros, I.; Liakakos, T.

Journal of the American College of Nutrition 2021: 1-9

2021

ISSN/ISBN: 0731-5724
PMID: 33704025
DOI: 10.1080/07315724.2021.1880986
Accession: 072340583

Full-Text Article emailed within 0-6 h
Payments are secure & encrypted
Powered by Stripe
Powered by PayPal

Summary
Disease-related malnutrition is a debilitating condition frequently observed in patients with cancer. The aim of the current study was to prospectively examine postoperative changes in nutritional and functional status of patients undergoing surgery for gastric, esophageal, and gastroesophageal junction cancer. Participants were prospectively recruited from September 2015 to September 2019. The assessment of malnutrition was based on the Patient-Generated Subjective Global Assessment tool. The functional assessment included the evaluation of muscle strength and physical performance, while muscle mass assessment was based on Skeletal Muscle Mass Index (SMI) derived from the analysis of computed tomography scans. The follow up of patients was scheduled at six months postoperatively. A total of 98 patients were analyzed. Mean patient age was 60.79 ± 10.19 years and 80.6% were males. The mean unintentional weight loss at 6 months was 11.7 ± 8.0%. Patients who underwent McKeown esophagectomy reported the greatest weight loss postoperatively (16.2 ± 9.6%), whereas the lowest rate of weight loss was observed in patients who underwent partial gastrectomy (5.6 ± 6.7%). The rate of severe malnutrition declined at six months postoperatively (39.7% vs 27%). Muscle strength and physical performance were significantly deteriorated at 6 months postoperatively, except for the group of partial gastrectomy, while SMI significantly decreased in all groups of patients except for McKewon esophagectomy group. Finally, the prevalence of low muscle mass increased significantly from 43.5% in the preoperative period to 66.7% at the follow-up. Our study revealed a significant deterioration in gastroesophageal cancer patient nutritional and functional status at six months postoperatively. The high prevalence of malnutrition and low muscle mass requires systematic follow-up and multidirectional monitoring in order to ensure the successful rehabilitation of these patients.

References

Lidoriki, I.; Mylonas, K.S.; Syllaios, A.; Vergadis, C.; Stratigopoulou, P.; Marinos, G.; Mastoraki, A.; Karavokyros, I.; Schizas, D. 2022: The Impact of Nutritional and Functional Status on Postoperative Outcomes following Esophageal Cancer Surgery Nutrition and Cancer 74(8): 2846-2858
Bozzetti, F.; Gianotti, L.; Braga, M.; Di Carlo, V.; Mariani, L. 2007: Postoperative complications in gastrointestinal cancer patients: the joint role of the nutritional status and the nutritional support Clinical Nutrition 26(6): 698-709
Sato, H. 1986: The use of the nutritional assessment index to assess preoperative and postoperative nutritional status in patients with esophageal cancer Ogoshi, S. Okada (ed.). Excerpta Medica International Congress Series, No. 649. Parenteral And Enteral Hyperalimentation; International Symposium, Kochi, Japan: 16-17, . Xv 376p. Excerpta Medica: Amsterdam, Netherlands; New York, N.y., Usa; Elsevier Science Publishers B.v: Amsterdam, Netherlands (dist. In The Usa And Canada By Elsevier Science Publishing Co. Inc: New York, N.y., Usa). Illus. 26-42, 1984, 1985
Yoshida, N.; Baba, Y.; Shigaki, H.; Harada, K.; Iwatsuki, M.; Kurashige, J.; Sakamoto, Y.; Miyamoto, Y.; Ishimoto, T.; Kosumi, K.; Tokunaga, R.; Imamura, Y.; Ida, S.; Hiyoshi, Y.; Watanabe, M.; Baba, H. 2016: Preoperative Nutritional Assessment by Controlling Nutritional Status (CONUT) is Useful to estimate Postoperative Morbidity After Esophagectomy for Esophageal Cancer World Journal of Surgery 40(8): 1910-1917
Ding, D.; Feng, Y.; Song, B.; Gao, S.; Zhao, J. 2015: Effects of preoperative and postoperative enteral nutrition on postoperative nutritional status and immune function of gastric cancer patients Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology 26(2): 181-185
Lidoriki, I.; Schizas, D.; Mpaili, E.; Michalinos, A.; Mpoura, M.; Kapelouzou, A.; Liakakos, T. 2018: Ps02.179: Nutritional Status Differences between Young and Elderly Patients Undergoing Surgery for Esophageal and Gastroesophageal Junction Cancer Diseases of the Esophagus 31(13): 172-173
Nakano, T.; Kamiya, K.; Kamei, T.; Taniyama, Y.; Sakurai, T.; Sato, C.; Fukutomi, T.; Ozawa, Y.; Ohuchi, N. 2015: SUN-LB041: Preoperative Prediction on Postoperative Complications and Prognosis by Nutritional Status Assessed by Controlling Nutritional Status (CONUT) Score Clinical Nutrition 34: S249-S250
Schrader, E.; Baumgärtel, C.; Gueldenzoph, H.; Stehle, P.; Uter, W.; Sieber, C.C.; Volkert, D. 2014: Nutritional status according to Mini Nutritional Assessment is related to functional status in geriatric patients--independent of health status Journal of Nutrition Health and Aging 18(3): 257-263
Santos, C.; Santos, I.; Mendes, L.; Mansinho, H. 2020: Nutritional Status and Functional Status of the Pancreatic Cancer Patients and the Impact of Adjacent Symptoms Clinical Nutrition ESPEN 40: 661-662
Santos, I.; Mendes, L.; Mansinho, H.; Santos, C.A. 2021: Nutritional status and functional status of the pancreatic cancer patients and the impact of adjacent symptoms Clinical Nutrition 40(11): 5486-5493
Santos, C.; Santos, I.; Mendes, L.; Ferreira, C.; Mansinho, H. 2019: SUN-PO083: Nutritional Status, Functional Status and Quality of Life – what is the Impact on Cancer Patients? Clinical Nutrition 38: S89-S90
Santos, Iês.Miranda.; Mendes, L.; Carolino, E.; Santos, C.Adriana. 2020: Nutritional Status, Functional Status, and Quality of Life - What is the Impact and Relationship on Cancer Patients? Nutrition and Cancer 2020: 1-14
Bagan, P.; Berna, P.; De Dominicis, F.; Das Neves Pereira, J.C.; Mordant, P.; De La Tour, B.; Le Pimpec-Barthes, F.; Riquet, M. 2013: Nutritional status and postoperative outcome after pneumonectomy for lung cancer Annals of Thoracic Surgery 95(2): 392-396
Pañella, L.; Jara, M.; Cornejo, M.; Lastra, X.; Contreras, M.ía.G.; Alfaro, K.; De La Maza, M.ía.P.ía. 2014: Nutritional status and postoperative complications in patients with digestive cancer Revista Medica de Chile 142(11): 1398-1406
Yu, G.; Chen, G.; Huang, B.; Shao, W.; Zeng, G. 2013: Effect of early enteral nutrition on postoperative nutritional status and immune function in elderly patients with esophageal cancer or cardiac cancer Chinese Journal of Cancer Research 25(3): 299-305
Beltran Chaidez, Y.L.; Dominguez Garcia, M.V.; Flores Merino, M.V.; Reyes Barretero, D.Y.; de Anda Torres, V.Y.; Jaimes Alpizar, E. 2018: Association between nutritional status and postoperative evolution in patients with gastrointestinal cancer Clinical Nutrition 37: S205-S206
Wu, L.-m.; Zhou, F.-r.; Lin, Q.-f.; Li, H.; Li, L.-h. 2011: Impact of nutritional status on postoperative outcomes for patients with colorectal cancer Zhonghua Wei Chang Wai Ke Za Zhi 14(4): 271-274
Hatada, T.; Miki, C. 2000: Nutritional status and postoperative cytokine response in colorectal cancer patients Cytokine 12(9): 1331-1336
Lidoriki, I.; Schizas, D. 2018: Are body mass index and performance status enough to assess the nutritional and functional status of elderly patients undergoing gastric cancer surgery? Surgery Today 48(12): 1100-1101
Ścisło, L.; Bodys-Cupak, I.; Walewska, E.żb.; Kózka, M. 2022: Nutritional Status Indicators as Predictors of Postoperative Complications in the Elderly with Gastrointestinal Cancer International Journal of Environmental Research and Public Health 19(20)