Polysomnographic characteristics of patients with heart failure combined with sleep apnea: a systematic review and meta-analysis

Yu, F.; Sun, Y.; Ye, S.; Li, Z.; Yang, D.; Zheng, R.; Guo, S.; Zhang, X.; Zhao, C.; Zhang, M.; Zhao, G.; Ai, S.; Yu, F; Sun, Y; Ye, S; Li, Z; Yang, D; Zheng, R; Guo, S; Zhang, X; Zhao, C; Zhang, M; Zhao, G; Ai, S

Home

>

Section

>

Chapter

Polysomnographic characteristics of patients with heart failure combined with sleep apnea: a systematic review and meta-analysis

Yu, F.; Sun, Y.; Ye, S.; Li, Z.; Yang, D.; Zheng, R.; Guo, S.; Zhang, X.; Zhao, C.; Zhang, M.; Zhao, G.; Ai, S.

Sleep Medicine 131: 106486

2025

ISSN/ISBN: 1878-5506

PMID: 40199034

Accession: 093968031

Article/Abstract emailed within 1 workday

Payments are secure & encrypted

Summary

Objective sleep parameters in patients with HF and their comorbidity with sleep-disordered breathing (SDB) are not fully understood. We aimed to investigate the polysomnography-measured sleep characteristics in HF patients using a systematic review and meta-analysis. PubMed, Embase, and Web of Science databases were searched for studies on PSG in HF patients. Meta-analyses were conducted to compare PSG parameters between HF patients and Non-HF, HF patients with and without SDB, HF patients with different types of SDB, and HF patients before and after SDB treatments. HF patients showed decreased sleep efficiency (MD = -7.5 %, 95 %CI: [-10.8 %, -4.1 %], P < 0.001) and reduced slow wave sleep (MD = -3.2 %, 95 %CI: [-5.7 %, -0.7 %], P = 0.013) compared with those without HF. With comorbid SDB, HF patients experienced further decreases in sleep efficiency and total sleep time, and disruptions in sleep architecture, including decreased rapid-eye-movement sleep (MD = -3.4 %, 95 %CI: [-6.2 %, -0.5 %], P = 0.020) and SWS (MD = -3.1 %, 95 %CI: [-4.1 %, -2.1 %], P < 0.001). HF patients showed poorer sleep continuity and less restorative sleep. Additionally, SDB was associated with poor objective sleep architecture in HF patients, indicated by a decrease in the percentage of deep sleep and an increase in sleep fragmentation. SDB treatments, such as adaptive servo-ventilation (ASV) and continuous positive airway pressure (CPAP), were associated with improved sleep quality and quantity in HF patients with SDB.

Polysomnographic characteristics of patients with heart failure combined with sleep apnea: a systematic review and meta-analysis

Yu, F.; Sun, Y.; Ye, S.; Li, Z.; Yang, D.; Zheng, R.; Guo, S.; Zhang, X.; Zhao, C.; Zhang, M.; Zhao, G.; Ai, S.

Sleep Medicine 131: 106486

2025

Article/Abstract emailed within 1 workday

Summary

References